Author, as appears in the article.: Marcé, R. M. ; Fontanals, N. ; Borrull, F.

Department: Química Analítica i Química Orgànica

URV's Author/s: MARCÉ RECASENS, ROSA MARIA; Fontanals, N. ; BORRULL BALLARÍN, FRANCESC

Keywords: Synthetic cathinones Solid-phase extraction Weak cation-exchange

Abstract: Synthetic cathinones have become popular in recent years, which would explain why their determination in influent sewage samples has already been documented. In the present study a method based on solid-phase extraction followed by liquid chromatography and high resolution mass spectrometry is developed, validated and applied to determine twelve cathinones and one of their metabolites in different environmental samples including influent and effluent sewage and river water. Two cation-exchange sorbents (Oasis MCX and Oasis WCX) were compared, with better results achieved with Oasis WCX in terms of apparent recoveries (70–100%) and matrix effects (lower than −34%). The method was validated with effluent sewage samples providing suitable figures of merit, with method quantification limits ranging from 1 ng/L to 5 ng/L and method detection limits from 0.1 ng/L to 0.5 ng/L for all the compounds. Of the different cathinones studied, three, namely methylone, mephedrone metabolite and methylenedioxypyrovalerone, were quantified at concentration levels of low ng/L in each of the different samples analysed, while a number of the other cathinones were also detected in some of the samples.

Research group: Grup de Cromatografia. Aplicacions Mediambientals

Thematic Areas: Química Química Chemistry

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0021-9673

Author identifier: 0000-0002-5667-2899; ; 0000-0003-2718-9336

Record's date: 2018-02-28

Last page: 73

Journal volume: 1524

Papper version: info:eu-repo/semantics/acceptedVersion

Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0021967317314590?via%3Dihub

Funding program: plan; Excelencia; CTQ2014-52617-P)

Article's DOI: 10.1016/j.chroma.2017.10.002

Entity: Universitat Rovira i Virgili

Journal publication year: 2017

First page: 66

Publication Type: Article Artículo Article