Author, as appears in the article.: Borrull, F. ; Nuñez, M.; Fontanals, N. ; Pocurull, E.

Department: Química Analítica i Química Orgànica

URV's Author/s: BORRULL BALLARÍN, FRANCESC; Nuñez, M.; Fontanals, N. ; POCURULL AIXALA, EVA

Keywords: High resolution mass spectrometry Pressurised liquid extraction IODINATED X-RAY CONTRAST MEDIA

Abstract: Iodinated X-ray contrast media (ICM-XR) are a group of pharmaceuticals widely used in medicine. Due to their ow biodegradation rate, which makes their removal at wastewater treatment plants difficult, and the high doses at which they are administered, they have been detected in aquatic environments. In the present paper, a method for the quantitative determination of a group of ICM-XR in different fish species was developed and validated for the first time. Two extraction techniques were compared: pressurised liquid extraction (PLE) and QuECh- ERS (Quick, Easy, Cheap, Effective, Rugged and Safe), with PLE being selected, followed by liquid chromatography-high resolution mass spectrometry. In addition, several clean-up strategies were evaluated. The optimised method provided PLE recoveries ranging from 60% to 88% and limits of detection ranging from 5 ng/g to 25 ng/g (dry weight). The method was applied in order to evaluate the presence of the selected ICM-XR in different fish species.

Research group: Grup de Cromatografia. Aplicacions Mediambientals

Thematic Areas: Chemistry Química Química

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0039-9140

Author identifier: 0000-0003-2718-9336; ; ; 0000-0001-5123-995X

Record's date: 2018-03-05

Last page: 7

Journal volume: 163

Papper version: info:eu-repo/semantics/acceptedVersion

Link to the original source: https://www.sciencedirect.com/science/article/pii/S0039914016308669?via%3Dihub

Funding program: plan; CTQ 2014-52617-P) plan; CTQ2011-24179

Article's DOI: 10.1016/j.talanta.2016.11.004

Entity: Universitat Rovira i Virgili

Journal publication year: 2017

First page: 1

Publication Type: Article Artículo Article