Author, as appears in the article.: Andrade, F.J.; Parrilla, M.; Cánovas, R.

Department: Química Analítica i Química Orgànica

URV's Author/s: ANDRADE , FRANCISCO JAVIER; Parrilla, M.; Cánovas, R.

Abstract: A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of -119±8 mV·decade-1, a linear range that spans from 10-4M to 10-2.5 M and a limit of detection of 10-4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.

Research group: Grup de Quimiometria, Qualimetria i Nanosensors

Thematic Areas: Química Química Chemistry

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0956-5663

Author identifier: 0000-0003-1199-2837; 0000-0002-1344-8432; 0000-0001-9552-535X

Record's date: 2018-04-30

Papper version: info:eu-repo/semantics/submittedVersion

Link to the original source: https://www.sciencedirect.com/science/article/pii/S0956566316311745?via%3Dihub

Funding program: plan; CTQ2013-46464-R altres; EU-Marie Curie Grant; PCIG09-GA-2011-293538 altres; Gencat fellowship; FI; FI_B 00079 altres; URV Martí i Franqués; PMF-PIPF; 2013PMF-PIPF-16

Article's DOI: 10.1016/j.bios.2016.11.034

Entity: Universitat Rovira i Virgili

Journal publication year: 2016

Publication Type: Article Artículo Article