Articles producció científica> Medicina i Cirurgia

Anthocyanin Tissue Bioavailability in Animals: Possible Implications for Human Health. A Systematic Review

  • Identification data

    Identifier: PC:3440
    Handle: http://hdl.handle.net/20.500.11797/PC3440
  • Authors:

    Sandoval-Ramírez, Berner Andrée
    Catalán, Úrsula
    Fernández-Castillejo, Sara
    Rubió, Laura
    Macià, Alba
    Solà, Rosa
  • Others:

    Author, as appears in the article.: Sandoval-Ramírez, Berner Andrée; Catalán, Úrsula; Fernández-Castillejo, Sara; Rubió, Laura; Macià, Alba; Solà, Rosa
    Department: Medicina i Cirurgia
    URV's Author/s: SANDOVAL RAMÍREZ, BERNER ANDRÉE; CATALÁN SANTOS, ÚRSULA; FERNÁNDEZ CASTILLEJO, SARA; Rubió, Laura; Macià, Alba; SOLÀ ALBERICH, ROSA MARIA
    Keywords: anthocyanins mechanism-of-action healthcare
    Abstract: Anthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13 publications met inclusion criteria. Extracted information included animal model employed, administration route, doses, analysis method, and ACN concentration values in tissues. Total ACN concentrations were detected in mice kidney (2.17 × 105 pmol/g), liver (1.73 × 105 pmol/g), heart (3.6 × 103 pmol/g), and lung (1.16 × 105 pmol/g); and in pig brain (6.08 × 103 pmol/g). ACNs showed a predominance of parent ACNs in long-term experiments versus an ACN metabolite predominance in short-term experiments. ACNs detected in animal tissues, such as cyanidin-3-glucoside, suggest it may have an important role in human health. This information could be useful to determine proper ACN-intake biomarkers in biological samples in futures studies.
    Research group: Unitat de Recerca de Lípids i Arteriosclerosi
    Thematic Areas: Ciències de la salut Ciencias de la salud Health sciences
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0021-8561
    Author identifier: 0000-0002-6242-922X; 0000-0001-8884-9823; 0000-0002-8109-9713; 0000-0001-8973-2942; 0000-0001-6091-5606; 0000-0002-8359-235X
    Record's date: 2019-03-21
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://pubs.acs.org/doi/10.1021/acs.jafc.8b04014
    Funding program: plan; AppleCOR; AGL2016-76943-C2-2-R
    Article's DOI: 10.1021/acs.jafc.8b04014
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2018
    Publication Type: Article Artículo Article
  • Keywords:

    Salut
    Fenols
    anthocyanins
    mechanism-of-action
    healthcare
    Ciències de la salut
    Ciencias de la salud
    Health sciences
    0021-8561
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