Author, as appears in the article.: Vilaprinyo, Ester; Gispert, Rosa; Martinez-Alonso, Montserrat; Carles, Misericordia; Pla, Roger; Espinas, Josep-Alfons; Rue, Montserrat;

Department: Economia Medicina i Cirurgia

URV's Author/s: Carles Lavila, Misericòrdia / Espinas Pinol, Josep Alfons / Pla Farnòs, Roger Jesús

Keywords: Riscos competitius Cáncer de mama

Abstract: Breast cancer mortality has experienced important changes over the last century. Breast cancer occurs in the presence of other competing risks which can influence breast cancer incidence and mortality trends. The aim of the present work is: 1) to assess the impact of breast cancer deaths among mortality from all causes in Catalonia (Spain), by age and birth cohort and 2) to estimate the risk of death from other causes than breast cancer, one of the inputs needed to model breast cancer mortality reduction due to screening or therapeutic interventions.The multi-decrement life table methodology was used. First, all-cause mortality probabilities were obtained by age and cohort. Then mortality probability for breast cancer was subtracted from the all-cause mortality probabilities to obtain cohort life tables for causes other than breast cancer. These life tables, on one hand, provide an estimate of the risk of dying from competing risks, and on the other hand, permit to assess the impact of breast cancer deaths on all-cause mortality using the ratio of the probability of death for causes other than breast cancer by the all-cause probability of death.There was an increasing impact of breast cancer on mortality in the first part of the 20th century, with a peak for cohorts born in 1945-54 in the 40-49 age groups (for which approximately 24% of mortality was due to breast cancer). Even though for cohorts born after 1955 there was only information for women under 50, it is also important to note that the impact of breast cancer on all-cause mortality decreased for those cohorts.We have quantified the effect of removing breast cancer mortality in different age groups and birth cohorts. Our results are consistent with US findings. We also have obtained an estimate of the risk of dying from competing-causes mortality, which will be used in the assessment of the effect of mammography screening on breast cancer mortality in Catalonia.

Thematic Areas: Saúde coletiva Química Planejamento urbano e regional / demografia Oncology Odontología Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Genetics Farmacia Ensino Engenharias iii Engenharias ii Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Ciência da computação Cancer research Biotecnología Biodiversidade Administração, ciências contábeis e turismo

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 14712407

Author's mail: rogerjesus.pla@urv.cat misericordia.carles@urv.cat

Author identifier: 0000-0002-3727-8933 0000-0003-3796-3014

Record's date: 2023-02-18

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-8-331

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Bmc Cancer. 8 331-

APA: Vilaprinyo, Ester; Gispert, Rosa; Martinez-Alonso, Montserrat; Carles, Misericordia; Pla, Roger; Espinas, Josep-Alfons; Rue, Montserrat; (2008). Competing risks to breast cancer mortality in Catalonia. Bmc Cancer, 8(), 331-. DOI: 10.1186/1471-2407-8-331

Article's DOI: 10.1186/1471-2407-8-331

Entity: Universitat Rovira i Virgili

Journal publication year: 2008

Publication Type: Journal Publications