Author, as appears in the article.: Sánchez-Villegas A; Álvarez-Pérez J; Toledo E; Salas-Salvadó J; Ortega-Azorín C; Zomeño MD; Vioque J; Martínez JA; Romaguera D; Pérez-López J; López-Miranda J; Estruch R; Bueno-Cavanillas A; Arós F; Tur JA; Tinahones FJ; Lecea O; Martín V; Ortega-Calvo M; Vázquez C; Pintó X; Vidal J; Daimiel L; Delgado-Rodríguez M; Matía P; Corella D; Díaz-López A; Babio N; Muñoz MÁ; Fitó M; de la Hera MG; Abete I; García-Rios A; Ros E; Ruíz-Canela M; Martínez-González MÁ; Izquierdo M; Serra-Majem L

Department: Bioquímica i Biotecnologia

e-ISSN: 2072-6643

URV's Author/s: Babio Sánchez, Nancy Elvira / Díaz López, Andres / Salas Salvadó, Jorge

Keywords: Omega-3 Fish Eicosapentaenoic acid Docosahexaenoic acid Depression fish eicosapentaenoic acid docosahexaenoic acid depression

Abstract: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. Background: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (ω-3 PUFA) intake, and depression prevalence. Methods: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and ω-3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and ω-3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) ω-3 PUFA intake and depressive symptoms. Results: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63–0.94), 0.71 (0.58–0.87), and 0.78 (0.64–0.96), respectively, and p for trend = 0.759. Moderate intake of total LC ω-3 PUFA (approximately 0.5–1 g/day) was significantly associated with a lower prevalence of depression. Conclusion: In our study, moderate fish and LC ω-3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship.

Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 20726643

Author's mail: andres.diaz@urv.cat nancy.babio@urv.cat jordi.salas@urv.cat

Author identifier: 0000-0002-7500-5629 0000-0003-3527-5277 0000-0003-2700-7459

Record's date: 2023-02-18

Journal volume: 10

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.mdpi.com/2072-6643/10/12/2000

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Nutrients. 10 (12):

APA: Sánchez-Villegas A; Álvarez-Pérez J; Toledo E; Salas-Salvadó J; Ortega-Azorín C; Zomeño MD; Vioque J; Martínez JA; Romaguera D; Pérez-López J; López-M (2018). Seafood consumption, omega-3 fatty acids intake, and life-time prevalence of depression in the PREDIMED-plus trial. Nutrients, 10(12), -. DOI: 10.3390/nu10122000

Article's DOI: 10.3390/nu10122000

Entity: Universitat Rovira i Virgili

Journal publication year: 2018

Publication Type: Journal Publications