Author, as appears in the article.: Brenner B.M., Charlton J., Luyckx V., Manfellotto D., Perico N., Remuzzi G., Somaschini M., Valensise H., Adu D., Allegaert K., Benedetto C., Cetin I., Chevalier R., Cortinovis M., D'Anna R., Duvekot J., Escribano J., Fanos V., Ferrazzi E., Frusca T., Glassock R.J., Gyselaers W., Mecacci F., Montini G., Osmond C., Ramenghi L., Romagnani P., Santoro A., Simeoni U., Steegers E.A.P., Vikse B.E.

Department: Medicina i Cirurgia

URV's Author/s: Escribano Subías, Joaquín

Keywords: Small for gestational age Programmed risk of kidney disease Programmed risk of hypertension Preterm birth Nephron number Neonatal acute kidney injury Maternal nutrition Low birth weight Intrauterine growth restriction Infant and child nutrition programmed risk of kidney disease programmed risk of hypertension preterm birth nephron number neonatal acute kidney injury maternal nutrition low birth weight intrauterine growth restriction infant and child nutrition

Abstract: Hypertension and chronic kidney disease (CKD) have a significant impact on global morbidity and mortality. The Low Birth Weight and Nephron Number Working Group has prepared a consensus document aimed to address the relatively neglected issue for the developmental programming of hypertension and CKD. It emerged from a workshop held on April 2, 2016, including eminent internationally recognized experts in the field of obstetrics, neonatology, and nephrology. Through multidisciplinary engagement, the goal of the workshop was to highlight the association between fetal and childhood development and an increased risk of adult diseases, focusing on hypertension and CKD, and to suggest possible practical solutions for the future. The recommendations for action of the consensus workshop are the results of combined clinical experience, shared research expertise, and a review of the literature. They highlight the need to act early to prevent CKD and other related noncommunicable diseases later in life by reducing low birth weight, small for gestational age, prematurity, and low nephron numbers at birth through coordinated interventions. Meeting the current unmet needs would help to define the most cost-effective strategies and to optimize interventions to limit or interrupt the developmental programming cycle of CKD later in life, especially in the poorest part of the world.

Thematic Areas: Urology & nephrology Urology Physiology (medical) Physiology Odontología Nephrology Medicine (miscellaneous) Medicina ii Medicina i Interdisciplinar General medicine Farmacia Ciências biológicas ii Ciências biológicas i

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 00282766

Author's mail: joaquin.escribano@urv.cat

Author identifier: 0000-0002-5041-459X

Record's date: 2023-02-18

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.karger.com/Article/FullText/457967

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Nephron. 136 (1): 3-49

APA: Brenner B.M., Charlton J., Luyckx V., Manfellotto D., Perico N., Remuzzi G., Somaschini M., Valensise H., Adu D., Allegaert K., Benedetto C., Cetin I. (2017). The Impact of Kidney Development on the Life Course: A Consensus Document for Action The Low Birth Weight and Nephron Number Working Group. Nephron, 136(1), 3-49. DOI: 10.1159/000457967

Article's DOI: 10.1159/000457967

Entity: Universitat Rovira i Virgili

Journal publication year: 2017

Publication Type: Journal Publications