Author, as appears in the article.: Casanova-Martí À, Serrano J, Portune KJ, Sanz Y, Blay MT, Terra X, Ardévol A, Pinent M.
Department: Bioquímica i Biotecnologia
URV's Author/s: Ardèvol Grau, Anna / Blay Olivé, Maria Teresa / CASANOVA MARTÍ, ANGELA / Pinent Armengol, Montserrat / Terra Barbadora, Ximena
Keywords: Hashtag Etiqueta «#» @uroweb @residentesaeu @infoAeu
Abstract: Grape seed proanthocyanidin extract (GSPE) modulates several parameters involved in metabolic syndrome. GSPE is a mixture of compounds, some which are rapidly absorbed, while others remain in the lumen where they might have effects that are translated to the whole organism. Our aim was to decipher if the 8-day treatment of GSPE, previously shown to reduce food intake, induces changes in the microbiota and enterohormone secretion. The ratio of Firmicutes?:?Bacteroidetes was lower in the microbiota of GSPE-treated rats compared to controls, and differences in several taxonomic families and genera were observed. Such modulation led to a reduction in cecal butyrate content. GSPE also increased plasma glucagon-like-peptide-1 (GLP-1). Gallic acid did not induce major changes in the microbiota profile nor in GLP-1 secretion. Correlations between several microbiota taxa and plasma triacylglycerol, adiposity, and enterohormones were observed. Modulation of microbiota may be one of the mechanism by which GSPE impacts metabolic health.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biochemistry & molecular biology
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 29938270
Author's mail: ximena.terra@urv.cat montserrat.pinent@urv.cat mteresa.blay@urv.cat anna.ardevol@urv.cat
Author identifier: 0000-0003-1043-5844 0000-0003-3550-5378 0000-0002-6256-9847 0000-0003-0156-7538
Record's date: 2023-02-26
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://pubs.rsc.org/en/content/articlelanding/2018/FO/C7FO02028G#!divAbstract
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Food & Function. 9 (3): 1672-1682
APA: Casanova-Martí À, Serrano J, Portune KJ, Sanz Y, Blay MT, Terra X, Ardévol A, Pinent M. (2018). Grape seed proanthocyanidins influence gut microbiota and enteroendocrine secretions in female rats. Food & Function, 9(3), 1672-1682. DOI: 10.1039/c7fo02028g
Article's DOI: 10.1039/c7fo02028g
Entity: Universitat Rovira i Virgili
Journal publication year: 2018
Publication Type: Journal Publications