Author, as appears in the article.: Brasch J, Beck-Jendroschek V, Iturrieta-González I, Voss K, Gené J.

Department: Ciències Mèdiques Bàsiques

URV's Author/s: Gené Díaz, Josepa

Keywords: Taxonomy Scopulariopsis Phylogeny Granuloma Fungi Dermatomycosis phylogeny granuloma fungi dermatomycosis scopulariopsis

Abstract: A 60-year-old woman presented with a nodular granulomatous skin lesion on her right thumb. It had developed after inoculation of a splinter of wood. Because it was resistant to various therapies, the nodule was finally excised. Complete healing followed this surgery and a melanised filamentous fungus with scopulariopsis-like morphology was recovered from the dermal tissue. Fitting with no known species, the fungus was subjected to extensive morphological, physiological and genetic investigations. It was characterised by resistance to cycloheximide, growth at 37°C, branched conidiophores with cylindrical annellides in brush-like groups producing dark conidia in basipetal chains, and cleistothecia with ellipsoidal to slightly reniform ascospores. Genetically it clustered in a well-supported clade together with Microascus (M.) brunneosporus, Microascus chinensis, Microascus intricatus, Microascus longicollis, Microascus micronesiensis and Microascus onychoides, but formed an independent branch distant from the other Microascus species. Based on its unique genetic characteristics and morphological findings, the isolate is proposed as a new species, Microascus ennothomasiorum. Morphologically it differs from its phylogenetically closest species by its branched conidiophores and ascomata with a peridium of textura intricata. Our observation once again emphasises that dermal granulomas can be caused by uncommon fungi; diagnostics should therefore include appropriate mycological investigations.

Thematic Areas: Saúde coletiva Química Odontología Mycology Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Infectious diseases General medicine Farmacia Engenharias iv Engenharias ii Engenharias i Enfermagem Dermatology & venereal diseases Dermatology Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotecnología Biodiversidade Astronomia / física

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 09337407

Author's mail: josepa.gene@urv.cat

Author identifier: 0000-0001-6195-9299

Record's date: 2023-02-22

Papper version: info:eu-repo/semantics/acceptedVersion

Link to the original source: https://onlinelibrary.wiley.com/doi/abs/10.1111/myc.12861

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Mycoses. 62 (2): 157-164

APA: Brasch J, Beck-Jendroschek V, Iturrieta-González I, Voss K, Gené J. (2019). A human subcutaneous infection by Microascus ennothomasiorum sp. nov.. Mycoses, 62(2), 157-164. DOI: 10.1111/myc.12861

Article's DOI: 10.1111/myc.12861

Entity: Universitat Rovira i Virgili

Journal publication year: 2019

Publication Type: Journal Publications