Author, as appears in the article.: Iglesias-Carres L; Mas-Capdevila A; Bravo FI; Aragonès G; Arola-Arnal A; Muguerza B

Department: Bioquímica i Biotecnologia Bioquímica i Biotecnologia Bioquímica i Biotecnologia

URV's Author/s: Aragonès Bargalló, Gerard / Arola Arnal, Anna / Bravo Vázquez, Francisca Isabel / Muguerza Marquínez, Maria Begoña

Keywords: Rats Proanthocyanidin Plasma kinetics Phenylpropionic acid (pubchem cid: 107) Phenolic compounds Phase-ii metabolism P-coumaric acid (pubchem cid: 637542) Microbial metabolism Metabolites Malvidin-3-o-glucoside (pubchem cid: 443652) Juices In-vitro Homovanillic acid (pubchem cid: 1738) Hippuric acid (pubchem cid: 464) Geographical origin Flavonoids Epigallocatechin gallate (pubchem cid: 65064) Epicatechin (pubchem cid: 72276) Cyanidin-3-o-rutinoside (pubchem cid: 441674) Catechin (pubchem cid: 9064) Benzoic acid (pubchem cid: 243) Antioxidant activity Anthocyanins Absorption phenylpropionic acid (pubchem cid: 107) phenolic compounds phase-ii metabolism microbial metabolism malvidin-3-o-glucoside (pubchem cid: 443652) homovanillic acid (pubchem cid: 1738) hippuric acid (pubchem cid: 464) flavonoids epigallocatechin gallate (pubchem cid: 65064) epicatechin (pubchem cid: 72276) cyanidin-3-o-rutinoside (pubchem cid: 441674) catechin (pubchem cid: 9064) benzoic acid (pubchem cid: 243) anthocyanins

Abstract: © 2019 Elsevier Ltd The health-promoting functions of fruit phenolic compounds are mainly attributed to their metabolites. The organic cultivation of fruits is becoming increasingly popular. Thus, this study evaluates whether the differences in red Grenache grapes derived from organic culture conditions influence the bioavailability and metabolism of phenolic compounds in rats. Organic and nonorganic (conventional) red Grenache grapes (OG and CG, respectively) were characterized and administered to Wistar rats (65 mg gallic acid equivalents/kg bw). Serum was recollected at different time points, and the phenolic metabolites were quantified by HPLC-ESI-MS/MS. The results showed that organic cultivation increased the oligomeric proanthocyanidin and anthocyanidin contents and decreased the content of free flavanols and dietary fiber. The serum profile of OG-administered rats showed higher metabolite concentrations at 2 h and reduced metabolite concentration at 24 h compared with the CG-administered rats. Thus, this particular serum kinetic behavior might influence the bioactivity of their phenolic compounds.

Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar Geociências Food science & technology Food science Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Enfermagem Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, applied Biotecnología Biodiversidade Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo

ISSN: 03088146

Author's mail: gerard.aragones@urv.cat franciscaisabel.bravo@urv.cat begona.muguerza@urv.cat anna.arola@urv.cat

Author identifier: 0000-0002-6468-3088 0000-0001-7384-8588 0000-0001-6529-1345

Record's date: 2023-02-18

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Food Chemistry. 299 (UNSP 125092): 125092-

APA: Iglesias-Carres L; Mas-Capdevila A; Bravo FI; Aragonès G; Arola-Arnal A; Muguerza B (2019). A comparative study on the bioavailability of phenolic compounds from organic and nonorganic red grapes. Food Chemistry, 299(UNSP 125092), 125092-. DOI: 10.1016/j.foodchem.2019.125092

Article's DOI: 10.1016/j.foodchem.2019.125092

Entity: Universitat Rovira i Virgili

Journal publication year: 2019

Publication Type: Journal Publications