Author, as appears in the article.: González-Del-Hoyo M; Cediel G; Carrasquer A; Bonet G; Vásquez-Nuñez K; Boqué C; Alí S; Bardají A

Department: Medicina i Cirurgia

URV's Author/s: Bardají Ruiz, Alfredo

Keywords: Paroxysmal supraventricular tachycardia Outcomes Myocardial-infarction Mortality Management Emergency department Chest-pain Cardiac troponin Association Assay Arrhythmia cardiac troponin arrhythmia

Abstract: © 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. Background: Tachyarrhythmias are very common in emergency medicine, and little is known about the long-term prognostic implications of troponin I levels in these patients. Hypothesis: This study aimed to investigate the correlation of cardiac troponin I (cTnI) levels and long-term prognosis in patients admitted to the emergency department (ED) with a primary diagnosis of tachyarrhythmia. Methods: A retrospective cohort study was conducted between January 2012 and December 2013, enrolling patients admitted to the ED with a primary diagnosis of tachyarrhythmia and having documented cTnI measurements. Clinical characteristics and 5-year all-cause mortality were analyzed. Results: Of a total of 222 subjects with a primary diagnosis of tachyarrhythmia, 73 patients had elevated levels of cTnI (32.9%). Patients with elevated cTnI levels were older and presented significantly more cardiovascular risk factors. At the 5-year follow-up, mortality was higher among patients with elevated cTnI levels (log-rank test P < 0.001). In the multivariable Cox regression analysis, elevated cTnI was an independent predictor of all-cause death (hazard ratio, 1.95, 95% confidence interval: 1.08-3.50, P = 0.026), in addition to age and prior heart failure. Conclusion: Patients admitted to the ED with a primary diagnosis of tachyarrhythmia and high cTnI levels have higher long-term mortality rates than patients with low cTnI levels. cTnI is thus a biomarker with predictive capacity for mortality in late follow-up, conferring utility in the risk stratification of this population.

Thematic Areas: Saúde coletiva Nutrição Medicine (miscellaneous) Medicina ii Medicina i General medicine Farmacia Enfermagem Ciências biológicas ii Cardiology and cardiovascular medicine Cardiac & cardiovascular systems

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 01609289

Author's mail: alfredo.bardaji@urv.cat

Author identifier: 0000-0003-1900-6974

Record's date: 2023-02-22

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/clc.23175

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Clinical Cardiology. 42 (5): 546-552

APA: González-Del-Hoyo M; Cediel G; Carrasquer A; Bonet G; Vásquez-Nuñez K; Boqué C; Alí S; Bardají A (2019). Prognostic implications of troponin I elevation in emergency department patients with tachyarrhythmia. Clinical Cardiology, 42(5), 546-552. DOI: 10.1002/clc.23175

Article's DOI: 10.1002/clc.23175

Entity: Universitat Rovira i Virgili

Journal publication year: 2019

Publication Type: Journal Publications