Author, as appears in the article.: Margalef J; Borràs C; Alegre S; Alberico E; Pàmies O; Diéguez M

Department: Química Física i Inorgànica

URV's Author/s: ALEGRE ARAGONÉS, SABINA / BORRÀS NOGUERA, CARLOTA / Diéguez Fernández, Montserrat / Pamies Ollé, Oscar

Keywords: Thioether-phosphite Substrate scope Rhodium Rh Phosphoroamidite Phosphoramidites Olefins Iridium-catalyzed hydrogenation Iridium Hydrogenation Highly enantioselective hydrogenation Enamides Complexes Asymmetric catalysis Amino

Abstract: © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim A large family of phosphite-thioether/selenoether ligands has been easily prepared from accessible L-(+)-tartaric acid and D-(+)-mannitol and applied in the M-catalyzed (M=Ir, Rh) asymmetric hydrogenation of a broad number of substrates (46 in total). Its highly modular architecture has been crucial to maximize the catalytic performance. Improving most of the reported approaches, this ligand family presents a broad substrate scope. By selecting the ligand parameters high enantioselectivities (ee's up to 99 %) have therefore been achieved in a broad range of both, functionalized and unfunctionalized substrates. Interestingly, both enantiomers of the hydrogenation products can be usually achieved by changing the ligand parameters.

Thematic Areas: Química Physical and theoretical chemistry Organic chemistry Medicina i Materiais Interdisciplinar Inorganic chemistry Farmacia Engenharias iv Engenharias iii Engenharias ii Engenharias i Ciências biológicas ii Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, physical Catalysis Biotecnología Astronomia / física

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 18673880

Author's mail: montserrat.dieguez@urv.cat oscar.pamies@urv.cat

Author identifier: 0000-0002-8450-0656 0000-0002-2352-8508

Last page: 2168

Record's date: 2023-02-18

Journal volume: 11

Papper version: info:eu-repo/semantics/acceptedVersion

Link to the original source: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cctc.201900132

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Chemcatchem. 11 (8): 2142-2168

APA: Margalef J; Borràs C; Alegre S; Alberico E; Pàmies O; Diéguez M (2019). Phosphite-thioether/selenoether Ligands from Carbohydrates: An Easily Accessible Ligand Library for the Asymmetric Hydrogenation of Functionalized and Unfunctionalized Olefins. Chemcatchem, 11(8), 2142-2168. DOI: 10.1002/cctc.201900132

Article's DOI: 10.1002/cctc.201900132

Entity: Universitat Rovira i Virgili

Journal publication year: 2019

First page: 2142

Publication Type: Journal Publications