Author, as appears in the article.: Martin-Lujan, Francisco; Catalin, Roxana-Elena; Salamanca-Gonzalez, Patricia; Sorli-Aguilar, Mar; Santigosa-Ayala, Antoni; Maria Valls-Zamora, Rosa; Martin-Vergara, Nuria; Canela-Armengol, Teresa; Arija-Val, Victoria; Sola-Alberich, Rosa;

Department: Medicina i Cirurgia

URV's Author/s: Arija Val, Maria Victoria / Solà Alberich, Rosa Maria

Keywords: Systemic inflammation Smoking Physical-activity questionnaire Patterns Obstructive pulmonary-disease Nutrition Meat consumption Intervention Health Antioxidants

Abstract: Data on the association between lung function and some dietary patterns have been published. However, it is not yet well known if whether the Mediterranean Diet (MD) pattern can preserve or improve lung function. Our purpose is to evaluate the effect of increased MD adherence on lung function in smokers. A multicenter, parallel, cluster-randomized, controlled clinical trial is proposed. A total of 566 active smokers (>10 packs-year), aged 25-75 years will be included, without previous respiratory disease and who sign an informed consent to participate. Twenty Primary Care Centres in Tarragona (Spain) will be randomly assigned to a control or an intervention group (1:1). All participants will receive advice to quit smoking, and the intervention group, a nutritional intervention (2 years) designed to increase MD adherence by: (1) annual visit to deliver personalized nutritional education, (2) annual telephone contact to reinforce the intervention, and (3) access to an online dietary blog. We will evaluate (annually for 2 years): pulmonary function by forced spirometry and MD adherence by a 14-item questionnaire and medical tests (oxidation, inflammation and consumption biomarkers). In a statistical analysis by intention-to-treat basis, with the individual smoker as unit of analysis, pulmonary function and MD adherence in both groups will be compared; logistic regression models will be applied to analyze their associations. We hope to observe an increased MD adherence that may prevent the deterioration of lung function in smokers without previous respiratory disease. This population may benefit from a dietary intervention, together with the recommendation of smoking cessation.

Thematic Areas: Respiratory system Pulmonary and respiratory medicine Public health, environmental and occupational health Primary health care Medicina i Family practice

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 20551010

Author's mail: victoria.arija@urv.cat rosa.sola@urv.cat

Author identifier: 0000-0002-1758-0975 0000-0002-8359-235X

Record's date: 2023-02-18

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.nature.com/articles/s41533-019-0153-7

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Npj Primary Care Respiratory Medicine. 29 (40): 40-

APA: Martin-Lujan, Francisco; Catalin, Roxana-Elena; Salamanca-Gonzalez, Patricia; Sorli-Aguilar, Mar; Santigosa-Ayala, Antoni; Maria Valls-Zamora, Rosa; M (2019). A clinical trial to evaluate the effect of the Mediterranean diet on smokers lung function. Npj Primary Care Respiratory Medicine, 29(40), 40-. DOI: 10.1038/s41533-019-0153-7

Article's DOI: 10.1038/s41533-019-0153-7

Entity: Universitat Rovira i Virgili

Journal publication year: 2019

Publication Type: Journal Publications