Author, as appears in the article.: Meza R Rivera-Andrade A Mendoza Montano C Dean M Prince M Carey TE Ogilvie GS Alvarez CS Sandoval-Ramírez BA Pineda A Bevilacqua K Gottschlich A Murchland AR

Department: Medicina i Cirurgia

URV's Author/s: SANDOVAL RAMÍREZ, BERNER ANDRÉE

Keywords: Public Health Epidemiology epidemiology

Abstract: © 2019 Author(s). Introduction Cervical cancer disproportionately burdens low-income and middle-income countries (LMICs) such as Guatemala. Self-collection testing for human papillomavirus (HPV) has been suggested as a form of cervical cancer screening to facilitate access in LMICs. This study assessed and compared the acceptability of self-collection HPV testing in two rural, indigenous and ethnically distinct communities in Guatemala: Santiago Atitlán, Sololá and Livingston, Izabal. Methods All participants, women between the ages of 18 and 60, completed a questionnaire. Eligible participants were also asked to self-collect a vaginal sample and complete a questionnaire regarding comfort and acceptability. Self-collected samples were tested for high-risk HPV using the real-time PCR Hybribio kit. Results In the indigenous community of Santiago Atitlán, of 438 age-eligible participants, 94% completed self-collection. Of those, 81% found it comfortable and 98% were willing to use it as a form of screening. In the multiethnic (Afro-Caribbean, indigenous) community of Livingston, of 322 age-eligible participants, 53% chose to self-collect. Among those who took the test, 83% found it comfortable and 95% were willing to use it as a form of screening. In Livingston, literacy (can read and/or write vs cannot read or write) was higher in women who chose to self-collect (prevalence ratio 2.25; 95% CI 1.38 to 3.68). Ethnicity, history of screening and reproductive history were not associated with willingness to self-collect in Livingston. Women in Santiago reported less prior use of healthcare than women in Livingston. Overall, 19% (106/549) of samples tested positive for high-risk HPV. Conclusion Among women willing to self-collect in rural and indigenous communities in Guatemala, self-collection for HPV testing is highly acceptable. However, willingness to try self-collection might vary across communities and settings. Women from a community that used less healthcare were more likely to choose self-collection. Further research is necessary to determine what factors influence a woman's choice to self-collect.

Thematic Areas: Medicine, General & Internal Medicine (Miscellaneous) General Medicine

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: bernerandree.sandoval@urv.cat

Author identifier: 0000-0002-6242-922X

ISSN: 20446055

Record's date: 2020-07-22

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://bmjopen.bmj.com/content/9/10/e029158

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: BMJ OPEN. (ISSN/ISBN: 20446055). 9(10): E029158

APA: Murchland A, Gottschlich A, Bevilacqua K, Pineda A, Sandoval-Ramírez B, Alvarez C, Ogilvie G, Carey T, Prince M, Dean M, Mendoza Montano C, Rivera-Andrade A, Meza R (2019). HPV self-sampling acceptability in rural and indigenous communities in Guatemala: A cross-sectional study. BMJ OPEN, 9(10), e029158-. DOI: 10.1136/bmjopen-2019-029158

Article's DOI: 10.1136/bmjopen-2019-029158

Entity: Universitat Rovira i Virgili

Journal publication year: 2019

Publication Type: Journal Publications