Author, as appears in the article.: Núñez M; Borrull F; Fontanals N; Pocurull E

Department: Química Analítica i Química Orgànica

URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / NÚÑEZ MARCÉ, MIREIA / Pocurull Aixala, Eva

Keywords: Pressurised liquid extraction Matrix effect Iodinated x-ray contrast media High resolution mass spectrometry Fish samples matrix effect iodinated x-ray contrast media high resolution mass spectrometry fish samples

Abstract: © 2016 Elsevier B.V. Iodinated X-ray contrast media (ICM-XR) are a group of pharmaceuticals widely used in medicine. Due to their low biodegradation rate, which makes their removal at wastewater treatment plants difficult, and the high doses at which they are administered, they have been detected in aquatic environments. In the present paper, a method for the quantitative determination of a group of ICM-XR in different fish species was developed and validated for the first time. Two extraction techniques were compared: pressurised liquid extraction (PLE) and QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe), with PLE being selected, followed by liquid chromatography-high resolution mass spectrometry. In addition, several clean-up strategies were evaluated. The optimised method provided PLE recoveries ranging from 60% to 88% and limits of detection ranging from 5 ng/g to 25 ng/g (dry weight). The method was applied in order to evaluate the presence of the selected ICM-XR in different fish species.

Thematic Areas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine General chemistry Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Chemistry (miscellaneous) Biotecnología Biodiversidade Biochemistry Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 00399140

Author's mail: nuria.fontanals@urv.cat francesc.borrull@urv.cat eva.pocurull@urv.cat nuria.fontanals@urv.cat

Author identifier: 0000-0002-7534-1964 0000-0003-2718-9336 0000-0001-5123-995X 0000-0002-7534-1964

Record's date: 2023-02-26

Papper version: info:eu-repo/semantics/acceptedVersion

Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0039914016308669

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Talanta. 163 1-7

APA: Núñez M; Borrull F; Fontanals N; Pocurull E (2017). Different sample treatments for the determination of ICM-XR in fish samples followed by LC-HRMS. Talanta, 163(), 1-7. DOI: 10.1016/j.talanta.2016.11.004

Article's DOI: 10.1016/j.talanta.2016.11.004

Entity: Universitat Rovira i Virgili

Journal publication year: 2017

Publication Type: Journal Publications