Author, as appears in the article.: Núñez M; Borrull F; Pocurull E; Fontanals N

Department: Química Analítica i Química Orgànica

URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / NÚÑEZ MARCÉ, MIREIA / Pocurull Aixala, Eva

Keywords: Sweeteners Pressurised liquid extraction Liquid chromatography-high resolution mass spectrometry Fish samples pressurised liquid extraction liquid chromatography-high resolution mass spectrometry fish samples

Abstract: © 2016 Elsevier B.V. An analytical method based on pressurised liquid extraction (PLE) followed by liquid chromatography-high resolution mass spectrometry (Orbitrap) was developed for the simultaneous determination of ten high-intensity sweeteners in fish samples. As the method was developed, the different PLE parameters were optimised and different clean-up strategies were evaluated, of which in-cell clean-up using alumina and on-cell clean-up with hexane were the most effective. PLE recoveries were between 43% and 94%. The method quantification limits were between 12.5 ng g−1 dry weight (d.w.) and 250 ng g−1 (d.w.) and the method detection limits between 2.5 ng g−1 (d.w.) and 125 ng g−1 (d.w.). Intra-day precision and inter-day precision were below 16% and 25%, respectively. Fish samples from different species were analysed and, saccharin was found below its method quantification limit in the species Scomber scombrus (Atlantic mackerel).

Thematic Areas: Zootecnia / recursos pesqueiros Química Organic chemistry Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Biochemistry Biochemical research methods Analytical chemistry

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 00219673

Author's mail: nuria.fontanals@urv.cat francesc.borrull@urv.cat eva.pocurull@urv.cat nuria.fontanals@urv.cat

Author identifier: 0000-0002-7534-1964 0000-0003-2718-9336 0000-0001-5123-995X 0000-0002-7534-1964

Record's date: 2023-06-09

Papper version: info:eu-repo/semantics/submittedVersion

Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0021967316316211

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Journal Of Chromatography a. 1479 32-39

APA: Núñez M; Borrull F; Pocurull E; Fontanals N (2017). Pressurised liquid extraction and liquid chromatography-high resolution mass spectrometry to determine high-intensity sweeteners in fish samples. Journal Of Chromatography a, 1479(), 32-39. DOI: 10.1016/j.chroma.2016.12.006

Article's DOI: 10.1016/j.chroma.2016.12.006

Entity: Universitat Rovira i Virgili

Journal publication year: 2017

Publication Type: Journal Publications