Author, as appears in the article.: Vila-Corcoles A, Hospital-Guardiola I, Ochoa-Gondar O, de Diego C, Salsench E, Raga X, Fuentes-Bellido CM.

Department: Medicina i Cirurgia

URV's Author/s: Fuentes Bellido, Cruz Maria

Abstract: The 23-valent polysaccharide pneumococcal vaccine (PPV-23) is recommended for elderly and high-risk people, although its effectiveness is controversial. Some studies have reported an increasing risk of acute vascular events among patients with pneumonia, and a recent case-control study has reported a reduction in the risk of myocardial infarction among patients vaccinated with PPV-23. Given that animal experiments have shown that pneumococcal vaccination reduces the extent of atherosclerotic lesions, it has been hypothesized that PPV-23 could protect against acute vascular events by an indirect effect preventing pneumonia or by a direct effect on oxidized low-density lipoproteins. The main objective of this study is to evaluate the clinical effectiveness of PPV-23 in reducing the risk of pneumonia and acute vascular events (related or nonrelated with prior pneumonia) in the general population over 60 years.

Thematic Areas: Zootecnia / recursos pesqueiros Sociología Serviço social Saúde coletiva Química Public, environmental & occupational health Public health, environmental and occupational health Psicología Planejamento urbano e regional / demografia Odontología Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar Geociências Farmacia Ensino Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência de alimentos Biotecnología Astronomia / física Antropologia / arqueologia Administração, ciências contábeis e turismo Administração pública e de empresas, ciências contábeis e turismo

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 1471-2458

Author's mail: cruzmaria.fuentes@urv.cat

Record's date: 2022-07-10

Journal volume: 10

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-10-25

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Bmc Public Health. 10 25-

APA: Vila-Corcoles A, Hospital-Guardiola I, Ochoa-Gondar O, de Diego C, Salsench E, Raga X, Fuentes-Bellido CM. (2010). Rationale and design of the CAPAMIS study: Effectiveness of pneumococcal vaccination against community-acquired pneumonia, acute myocardial infarction and stroke. Bmc Public Health, 10(), 25-. DOI: 10.1186/1471-2458-10-25

Article's DOI: 10.1186/1471-2458-10-25

Entity: Universitat Rovira i Virgili

Journal publication year: 2010

Publication Type: Journal Publications