Author, as appears in the article.: Boqué N; Tarro L; Rosi A; Torrell H; Saldaña G; Luengo E; Rachman Z; Pires A; Tavares NT; Pires AS; Botelho MF; Mena P; Scazzina F; Rio DD; Caimari A

Department: Medicina i Cirurgia

URV's Author/s: Tarro Sánchez, Lucía

Keywords: Youth obesity Young population Waist hip ratio Waist circumference Therapy effect Species composition Spain Software Single blind procedure Risk factor Randomized controlled trials as topic Randomized controlled trial (topic) Randomized controlled trial Quality of life Portugal Physical activity Patient education Oxidative stress Omics Obesity Nutrition Multicenter study (topic) Multicenter study Multicenter studies as topic Motivational interviewing Microbiota Metabolomics Metabolite Mediterranean diet Major clinical study Lythraceae Low fat diet Knowledge Italy Intestine flora Insulin resistance Inflammation Humans Human Healthy food products Health status Health education Gut microbiota Glucose Food intake Food frequency questionnaire Female Educational approach Documentation Dietary record Dietary compliance Diet, mediterranean Diet, fat-restricted Diet Demography Controlled study Clinical protocol Clinical outcome Cardiovascular risk factors Cardiovascular risk Cardiovascular disease Body weight Body mass Body height Body composition Blood pressure Biochemistry Article Advanced glycation end product Adult Adolescents Adolescent obesity Adolescent Adipose tissue

Abstract: Youth obesity is a strong predictor of adult obesity, which has well-known negative health consequences. Thus, addressing adult obesity requires tackling youth obesity. MED4Youth’s main objective is to strengthen the link between the Mediterranean Diet (MD) and the health benefits against youth obesity and associated cardiovascular disease (CVD) risk factors, identifying positive effects exerted by an MD including sourdough bread and healthy products from the Mediterranean basis (chickpeas/hummus, nuts, and pomegranate juice). For this purpose, a multicenter randomized controlled trial in which an MD-based intervention will be compared to a traditional low-fat diet intervention will be carried out with 240 overweight and obese adolescents (13–17 years) from Spain, Portugal, and Italy. Both interventions will be combined with an educational web-application addressed to engage the adolescents through a learning-through-playing approach, using both educational materials and games. To assess the interventions, adherence to the MD, dietary records, physical activity, food frequency, sociodemographic, and quality of life questionnaires as well as classical anthropometric and biochemical parameters will be evaluated. Furthermore, an omics approach will be performed to elucidate whether the interventions can shape the gut microbiota and gut-derived metabolites to gain knowledge on the mechanisms through which the MD can exert its beneficial effects. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Thematic Areas: Zootecnia / recursos pesqueiros Serviço social Saúde coletiva Química Public, environmental & occupational health Public health, environmental and occupational health Psicología Pollution Odontología Nutrição Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Health, toxicology and mutagenesis Geografía Geociências Farmacia Environmental sciences Ensino Engenharias ii Engenharias i Enfermagem Educação física Educação Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência da computação Biotecnología Biodiversidade Astronomia / física Administração pública e de empresas, ciências contábeis e turismo

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: lucia.tarro@urv.cat

Author identifier: 0000-0002-8323-3576

Record's date: 2023-02-19

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.mdpi.com/1660-4601/18/9/4841

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: International Journal Of Environmental Research And Public Health. 18 (9):

APA: Boqué N; Tarro L; Rosi A; Torrell H; Saldaña G; Luengo E; Rachman Z; Pires A; Tavares NT; Pires AS; Botelho MF; Mena P; Scazzina F; Rio DD; Caimari A (2021). Study protocol of a multicenter randomized controlled trial to tackle obesity through a mediterranean diet vs. A traditional low-fat diet in adolescents: The med4youth study. International Journal Of Environmental Research And Public Health, 18(9), -. DOI: 10.3390/ijerph18094841

Article's DOI: 10.3390/ijerph18094841

Entity: Universitat Rovira i Virgili

Journal publication year: 2021

Publication Type: Journal Publications