Repositori institucional URV
| URV's Author/s: | VALLS ZAMORA, ROSA MARIA; PEDRET FIGUEROLA, ANNA; FERNÁNDEZ CASTILLEJO, SARA; CATALÁN SANTOS, ÚRSULA; ROMEU FERRAN, MARTA; GIRALT BATISTA, MONTSERRAT; SOLÀ ALBERICH, ROSA MARIA; RUBIÓ, LAURA |
| Author, as appears in the article.: | Rosa-M. Valls; Marta Farràs; Anna Pedret; Sara Fernández-Castillejo ; Úrsula Catalán; Marta Romeu; Montse Giralt; Guillermo-T. Sáez ; Montserrat Fitó; Rafael de la Torre; María-Isabel Covas; María-José Motilva; Rosa Solà; Laura Rubió |
| Author's mail: | rosamaria.valls@urv.cat |
| Journal publication year: | 2017 |
| Publication Type: | Article |
| ISSN: | 1756-4646 |
| Abstract: | The aim of the present study was to assess whether different functional virgin olive oils (FVOOs) with varying phenolic compounds (PC) could protect the plasmatic fat-soluble vitamins, which in turn could improve the endothelial function. In order to select the optimal phenolic dose in the improvement of ischemic reactive hyperemia (IRH), a dose-response study (n = 12, healthy subjects) was performed and the enrichment of 500 mg PC/kg oil was selected. In a 3-week cross-over sustained study (n = 33 hypercholesterolemic subjects), the consumption of 25 mL/day of two phenol-enriched olive oils (one enriched with its own PC and another combined with thyme PC) increased IRH and plasma concentrations of retinol, β-cryptoxanthin and α-tocopherol, compared to a control virgin olive oil. A positive post-intervention correlation was observed for IRH values and HDL-c, β-cryptoxanthin, lutein and α-tocopherol. Results suggest that preservation of plasmatic fat-soluble vitamins by PC from FVOOS could partially explain the endothelial function benefits. |
| Article's DOI: | 10.1016/j.jff.2016.10.032 |
| Link to the original source: | https://www.sciencedirect.com/science/article/abs/pii/S1756464616303607 |
| Papper version: | info:eu-repo/semantics/acceptedVersion |
| licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
| Department: | Ciències Mèdiques Bàsiques Medicina i Cirurgia |
| Research group: | Unitat de Recerca de Lípids i Arteriosclerosi Farmacobiologia Cel.lular |
| Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Thematic Areas: | Health sciences |
| Keywords: | virgin olive oil Phenolic compounds endothelial function |
| Entity: | Universitat Rovira i Virgili |
| Record's date: | 2017-01-19 |
| First page: | 285 |
| Last page: | 292 |
| Journal volume: | 28 |
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| File | Description | Format | |
|---|---|---|---|
| DocumentPrincipal | DocumentPrincipal | application/pdf |
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