Repositori institucional URV
| URV's Author/s: | Victoria Hernando, Belen Alejos, Susana Monge, Juan berenguer |
| Author, as appears in the article.: | Hernando, V. Alejos, B. Monge, S. Berenguer, J. Anta, L. Vinuesa, D. Palacios, R. Muga, R. Moreno, S. Jarrin, I. and for CoRIS cohort |
| Journal publication year: | 2013 |
| ISSN: | 1471-2334 |
| Abstract: | Background Combination antiretroviral therapy (cART) has produced significant changes in mortality of HIV-infected persons. Our objective was to estimate mortality rates, standardized mortality ratios and excess mortality rates of cohorts of the AIDS Research Network (RIS) (CoRIS-MD and CoRIS) compared to the general population. Methods We analysed data of CoRIS-MD and CoRIS cohorts from 1997 to 2010. We calculated: (i) all-cause mortality rates, (ii) standardized mortality ratio (SMR) and (iii) excess mortality rates for both cohort for 100 person-years (py) of follow-up, comparing all-cause mortality with that of the general population of similar age and gender. Results Between 1997 and 2010, 8,214 HIV positive subjects were included, 2,453 (29.9%) in CoRIS-MD and 5,761 (70.1%) in CoRIS and 294 deaths were registered. All-cause mortality rate was 1.02 (95% CI 0.91-1.15) per 100 py, SMR was 6.8 (95% CI 5.9-7.9) and excess mortality rate was 0.8 (95% CI 0.7-0.9) per 100 py. Mortality was higher in patients with AIDS, hepatitis C virus (HCV) co-infection, and those from CoRIS-MD cohort (1997¿2003). Conclusion Mortality among HIV-positive persons remains higher than that of the general population of similar age and sex, with significant differences depending on the history of AIDS or HCV coinfection. |
| Article's DOI: | 10.1186/1471-2334-13-382 |
| Link to the original source: | http://www.biomedcentral.com/1471-2334/13/382 |
| Papper version: | info:eu-repo/semantics/publishedVersion |
| licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
| Department: | Ciències Mèdiques Bàsiques |
| Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Entity: | Universitat Rovira i Virgili. |
| First page: | 382 |
| Last page: | 388 |
| Journal volume: | 13 |
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