Transglutaminase 6 autoantibodies in neurological gluten-related affection suspected patients: validation as a diagnostic biomarker

Muñoz Blázquez, Aida

Belongs to TFG:SerieGeneralBBMO collection

TITLE:

Transglutaminase 6 autoantibodies in neurological gluten-related affection suspected patients: validation as a diagnostic biomarker - TFG:5124

Handle:

https://hdl.handle.net/20.500.11797/TFG5124

Student:	Muñoz Blázquez, Aida
Language:	en
Title in original language:	Transglutaminase 6 autoantibodies in neurological gluten-related affection suspected patients: validation as a diagnostic biomarker
Title in different languages:	Transglutaminase 6 autoantibodies in neurological gluten-related affection suspected patients: validation as a diagnostic biomarker
Keywords:	Transglutaminase 6 antibodies, gluten sensitivity, biomarker
Subject:	Biotecnologia
Abstract:	IgA autoantibodies against transglutaminase 6 (TG6-Ab) have been suggested as a diagnostic biomarker for neurological dysfunctions related to gluten sensitivity like gluten ataxia. The present study aims to test TG6-Ab levels in neurological affection-suspected patients and coeliac disease (CD) patients, to validate the test for its use in clinical practice. Methodology is based in an Enzyme-linked Immunosorbent Assay. Results recapitulate the prevalence of TG6-Ab in CD and neurological patients, although was obtained higher in healthy controls. TG6-Ab follow-up determinations seem to be a helpful diagnostic marker for neurological gluten-related dysfunctions together with previous clinical evaluation and classical gluten sensitivity tests.
Project director:	Gabaldó Barrios, Xavier
Department:	Bioquímica i Biotecnologia
Education area(s):	Bioquímica i Biologia Molecular
Entity:	Universitat Rovira i Virgili (URV)
TFG credits:	15
Creation date in repository:	2022-07-28
Work's public defense date:	2022-06-22
Academic year:	2021-2022
Confidenciality:	No
Subject areas:	Biochemistry and biotechnology
Access rights:	info:eu-repo/semantics/openAccess

Search your record at:

Available files
File	Description	Format
Memòria	Memory	application/pdf

All objects of this collection

Title:	Transglutaminase 6 autoantibodies in neurological gluten-related affection suspected patients: validation as a diagnostic biomarker
Coverage:	No
Type:	info:eu-repo/semantics/bachelorThesis
Contributor:	Gabaldó Barrios, Xavier
Subject:	Bioquímica i biotecnologia Biochemistry and biotechnology Bioquímica y biotecnología Biotecnologia
Date:	2022-06-22
Language:	en
Format:	Universitat Rovira i Virgili (URV)
Creator:	Muñoz Blázquez, Aida
Rights:	info:eu-repo/semantics/openAccess

Information