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TITLE:
Characterization of the Toxoplasma gondii infection in SH-SY5Y cells - TFG:6583

Student:Hidalgo Nieves, Sara
Language:en
Title in original language:Characterization of the Toxoplasma gondii infection in SH-SY5Y cells
Keywords:Toxoplasma gondii, SH-SY5Y, infection
Subject:Biotecnologia
Abstract:Toxoplasmosis is a disease that affects approximately 1/3 of the population worldwide and its major organ of infection is the brain. The majority of in vitro studies use human foreskin fibroblasts (HFF), but in this study SH-SY5Y cells are proposed as a neuronal model for this infection. In this work it has been seen that T. gondii in SH-SY5Y cells had a fastest life cycle than in HFF and the expansion of the infection and the infection rates were similar in both cultures. Also, the production of cytokines by SH-SY5Y cells seemed that decreased with time with T. gondii infection.
Project director:Rodríguez Gallego, Esther
Department:Bioquímica i Biotecnologia
Education area(s):Bioquímica i Biologia Molecular
Entity:Universitat Rovira i Virgili (URV)
Creation date in repository:2023-12-18
Work's public defense date:2023-06-21
Academic year:2022-2023
Confidenciality:No
Subject areas:Biochemistry and biotechnology
Access rights:info:eu-repo/semantics/openAccess
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