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TITLE:
Metabolomic profiling of breast cancer patients after treatments: insights into therapeutic response - TFG:6585
Handle: https://hdl.handle.net/20.500.11797/TFG6585

Student:Jiménez Aguilar, Juan Manuel
Language:en
Title in original language:Metabolomic profiling of breast cancer patients after treatments: insights into therapeutic response
Keywords:biomarkers, metabolic alterations, targeted metabolomics
Subject:Càncer
Abstract:This study aimed to investigate the effects of surgery, chemotherapy, and radiotherapy on breast cancer (BC) patients by analyzing their metabolome and identifying metabolic biomarkers for treatment response. Post-treatment samples showed progressive normalization of metabolites associated with nucleotide and carbohydrate metabolism. Surgery and radiotherapy significantly influenced BC patients' metabolome, potentially associated with cancer cell eradication. Moreover, the study identified potential biomarkers for BC diagnosis from plasma samples. Different treatments led to distinct metabolic profiles based on clinicopathological characteristics.
Project director:Hernandez Aguilera, Anna
Department:Bioquímica i Biotecnologia
Education area(s):Bioquímica i Biologia Molecular
Entity:Universitat Rovira i Virgili (URV)
Creation date in repository:2023-12-18
Work's public defense date:2023-06-21
Academic year:2022-2023
Confidenciality:No
Subject areas:Biochemistry and biotechnology
Access rights:info:eu-repo/semantics/openAccess
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