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TITLE:

A novel electrochemical immunosensor for in situ antibody quantification - TFM:1217
Handle:

https://hdl.handle.net/20.500.11797/TFM1217

Student:Oulad Ali El Hammouchi, Ahlam
Language:en
Title in original language:A novel electrochemical immunosensor for in situ antibody quantification
Title in different languages:A novel electrochemical immunosensor for in situ antibody quantification
Keywords:potentiometry, ELISA, sensors
Subject:Electroquimica
Abstract:Due to COVID-19, there has been an increase in the demand of Point-of-Care (POC) devices. In this work we introduce the first steps towards development of a novel POC device – an electrochemical immunosensor – that quantify in situ immunoglobulin gamma (IgG) in biological samples. We report a simple and low-cost methodology of construction of paper support-based Platinum sensors that use potentiometry for quantification. The recognition method is Enzyme-Linked Immunosorbent Assay (ELISA), through using glucose oxidase (GOX) linked antibodies. Potentiometric measurements were given based on the mixed potential mechanism. Moreover, an explanation of the sensors analytical performance, sensitivity and selectivity is provided.
Project director:Blondeau, Pascal Jean Claude Leon; Andrade, Francisco Javier
Department:Química Analítica i Química Orgànica
Education area(s):Nanociència, Materials i Processos - Tecnologia Química de Frontera 
Entity:Universitat Rovira i Virgili (URV)
Work's public defense date:2022-09-09
Academic year:2021-2022
Confidenciality:No
Subject areas:Biochemistry and biotechnology
APS:NO
Creation date in repository:2022-11-24
Access Rights:info:eu-repo/semantics/openAccess
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