Repositori institucional URV
Belongs to TFM:SerieGeneralNMT collection
TITLE:
Neuroinflammation, microglia, NAD+, type 1 diabetes mellitus, vitamin B3 - TFM:1413
Handle:
https://hdl.handle.net/20.500.11797/TFM1413
Student:
Torres Mendez, Jeimy Katherine
Language:
en
Title in original language:
Neuroinflammation, microglia, NAD+, type 1 diabetes mellitus, vitamin B3
Title in different languages:
Neuroinflammation, microglia, NAD+, type 1 diabetes mellitus, vitamin B3
Keywords:
neuroinflammation, NAD+, type 1 diabetes mellitus
Subject:
Nicotina
Abstract:
Diabetes mellitus is frequently linked to chronic neuroinflammation. Accumulating evidence suggest that activated microglia underlies diabetic neuropathy. Currently there are no specific treatments for diabetic neuropathy. NAD+ is a mandatory coenzyme for the action of several NAD+ consuming enzymes that are involved in the inflammatory response. Therefore, its replenishment was considered as a potential therapy to prevent neuroinflammation. In this context, nicotinamide (NAM), which is a precursor of NAD+, may have positive effects on diabetic neuroinflammation. We tested the hypothesis that increased bioavailability of NAM will attenuate activation of microglia in a mouse model of experimental diabetes mellitus type 1 (T1D)
Department:
Bioquímica i Biotecnologia
Education area(s):
Nutrició i Metabolisme
Entity:
Universitat Rovira i Virgili (URV)
Work's public defense date:
2022-06-20
Academic year:
2021-2022
Confidenciality:
Si
Subject areas:
Health sciences
APS:
NO
Creation date in repository:
2023-07-05
Access Rights:
info:eu-repo/semantics/openAccess
Coverage:
NO
Type:
info:eu-repo/semantics/masterThesis
Títol:
Neuroinflammation, microglia, NAD+, type 1 diabetes mellitus, vitamin B3
Subject:
Ciències de la salut
Health sciences
Ciencias de la salud
Nicotina
Date:
2022-06-20
Language:
en
Format:
Universitat Rovira i Virgili (URV)
Creator:
Torres Mendez, Jeimy Katherine
Rights:
info:eu-repo/semantics/openAccess
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