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TITLE:
Longitudinal changes in Mediterranean diet and transition between different obesity phenotypes - imarina:5097956

URV's Author/s:Babio Sánchez, Nancy Elvira / Díaz López, Andres / Salas Salvadó, Jorge
Author, as appears in the article.:Konieczna, J; Yanez, A; Monino, M; Babio, N; Toledo, E; Martinez-Gonzalez, M A; Sorli, J, V; Salas-Salvado, J; Estruch, R; Ros, E; Alonso-Gomez, A; Schroder, H; Lapetra, J; Serra-Majem, Ll; Pinto, X; Gutierrez-Bedmar, M; Diaz-Lopez, A; Gonzalez, J, I; Fito, M; Forga, L; Fiol, M; Romaguera, D
Author's mail:andres.diaz@urv.cat
jordi.salas@urv.cat
nancy.babio@urv.cat
Author identifier:0000-0002-7500-5629
0000-0003-2700-7459
0000-0003-3527-5277
Journal publication year:2020
Publication Type:Journal Publications
ISSN:02615614
APA:Konieczna, J; Yanez, A; Monino, M; Babio, N; Toledo, E; Martinez-Gonzalez, M A; Sorli, J, V; Salas-Salvado, J; Estruch, R; Ros, E; Alonso-Gomez, A; Sc (2020). Longitudinal changes in Mediterranean diet and transition between different obesity phenotypes. Clinical Nutrition, 39(3), 966-975. DOI: 10.1016/j.clnu.2019.04.002
Paper original source:Clinical Nutrition. 39 (3): 966-975
Abstract:© 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism Background & aims: Little is known about the impact of specific dietary patterns on the development of obesity phenotypes. We aimed to determine the association of longitudinal changes in adherence to the traditional Mediterranean diet (MedDiet) with the transition between different obesity phenotypes. Methods: Data of 5801 older men and women at high cardiovascular risk from PREDIMED trial were used. Adherence to MedDiet was measured with the validated 14p-Mediterranean Diet Adherence Screener (MEDAS). Using the simultaneous combination of metabolic health- and body size-related parameters participants were categorized into one of four phenotypes: metabolically healthy and abnormal obese (MHO and MAO), metabolically healthy and abnormal non-obese (MHNO and MANO). Cox regression models with yearly repeated measures during 5-year of follow-up were built with use of Markov chain assumption. Results: Each 2-point increase in MEDAS was associated with the following transitions: in MAO participants, with a 16% (95% CI 3–31%) greater likelihood of becoming MHO; in MHO participants with a 14% (3–23%) lower risk of becoming MAO; in MHNO participants with a 18% (5–30%) lower risk of becoming MHO. In MANO women, but not in men, MEDAS was associated with 20% (5–38%) greater likely of becoming MHNO (p for interaction by gender 0.014). No other significant associations were observed. Conclusions: Better adherence to the traditional MedDiet is associated with transitions to healthier phenotypes, promoting metabolic health improvement in MAO, MANO (only in women), and MHO, as well as protecting against obesity incidence in MHNO subjects.
Article's DOI:10.1016/j.clnu.2019.04.002
Link to the original source:https://www.clinicalnutritionjournal.com/article/S0261-5614(19)30157-8/abstract
Paper version:info:eu-repo/semantics/acceptedVersion
licence for use:https://creativecommons.org/licenses/by/3.0/es/
Department:Bioquímica i Biotecnologia
Bioquímica i Biotecnologia
Licence document URL:https://repositori.urv.cat/ca/proteccio-de-dades/
Thematic Areas:Saúde coletiva
Química
Odontología
Nutrition and dietetics
Nutrition & dietetics
Nutrição
Medicina iii
Medicina ii
Medicina i
Interdisciplinar
General medicine
Farmacia
Engenharias iv
Enfermagem
Educação física
Critical care and intensive care medicine
Ciências biológicas iii
Ciências biológicas ii
Ciências biológicas i
Ciência de alimentos
Biotecnología
Keywords:Transition probabilities
The predimed trial
Obesity phenotypes
Metabolically healthy obese
Metabolically abnormal non-obese
Mediterranean diet
the predimed trial
obesity phenotypes
metabolically healthy obese
metabolically abnormal non-obese
mediterranean diet
Entity:Universitat Rovira i Virgili
Record's date:2025-02-19
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