Repositori institucional URV
| URV's Author/s: | Bardají Ruiz, Alfredo / Bonet Pineda, Gil / Carrasquer Cucarella, Ana Maria |
| Author, as appears in the article.: | Gonzalez-Del-Hoyo, Maribel; Cediel, German; Carrasquer, Anna; Bonet, Gil; Vasquez-Nunez, Karla; Boque, Carme; Ali, Samuel; Bardaji, Alfredo |
| Author's mail: | gil.bonet@urv.cat anamaria.carrasquer@urv.cat anamaria.carrasquer@urv.cat alfredo.bardaji@urv.cat |
| Author identifier: | 0000-0003-1900-6974 |
| Journal publication year: | 2019 |
| Publication Type: | Journal Publications |
| ISSN: | 01609289 |
| APA: | Gonzalez-Del-Hoyo, Maribel; Cediel, German; Carrasquer, Anna; Bonet, Gil; Vasquez-Nunez, Karla; Boque, Carme; Ali, Samuel; Bardaji, Alfredo (2019). Prognostic implications of troponin I elevation in emergency department patients with tachyarrhythmia. Clinical Cardiology, 42(5), 546-552. DOI: 10.1002/clc.23175 |
| Paper original source: | Clinical Cardiology. 42 (5): 546-552 |
| Abstract: | © 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. Background: Tachyarrhythmias are very common in emergency medicine, and little is known about the long-term prognostic implications of troponin I levels in these patients. Hypothesis: This study aimed to investigate the correlation of cardiac troponin I (cTnI) levels and long-term prognosis in patients admitted to the emergency department (ED) with a primary diagnosis of tachyarrhythmia. Methods: A retrospective cohort study was conducted between January 2012 and December 2013, enrolling patients admitted to the ED with a primary diagnosis of tachyarrhythmia and having documented cTnI measurements. Clinical characteristics and 5-year all-cause mortality were analyzed. Results: Of a total of 222 subjects with a primary diagnosis of tachyarrhythmia, 73 patients had elevated levels of cTnI (32.9%). Patients with elevated cTnI levels were older and presented significantly more cardiovascular risk factors. At the 5-year follow-up, mortality was higher among patients with elevated cTnI levels (log-rank test P < 0.001). In the multivariable Cox regression analysis, elevated cTnI was an independent predictor of all-cause death (hazard ratio, 1.95, 95% confidence interval: 1.08-3.50, P = 0.026), in addition to age and prior heart failure. Conclusion: Patients admitted to the ED with a primary diagnosis of tachyarrhythmia and high cTnI levels have higher long-term mortality rates than patients with low cTnI levels. cTnI is thus a biomarker with predictive capacity for mortality in late follow-up, conferring utility in the risk stratification of this population. |
| Article's DOI: | 10.1002/clc.23175 |
| Link to the original source: | https://onlinelibrary.wiley.com/doi/full/10.1002/clc.23175 |
| Paper version: | info:eu-repo/semantics/publishedVersion |
| licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
| Department: | Medicina i Cirurgia |
| Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Thematic Areas: | Saúde coletiva Nutrição Medicine (miscellaneous) Medicina ii Medicina i General medicine Farmacia Enfermagem Ciências biológicas ii Cardiology and cardiovascular medicine Cardiac & cardiovascular systems |
| Keywords: | Up-regulation Troponin i Time factors Risk factors Risk assessment Retrospective studies Prognosis Predictive value of tests Paroxysmal supraventricular tachycardia Outcomes Myocardial-infarction Mortality Middle aged Management Male Humans Female Emergency service, hospital Emergency department Chest-pain Cardiac troponin Biomarkers Association Assay Arrhythmias, cardiac Arrhythmia Aged, 80 and over Aged cardiac troponin arrhythmia |
| Entity: | Universitat Rovira i Virgili |
| Record's date: | 2025-01-28 |
| Search you record at: |  |
| File | Description | Format | |
|---|---|---|---|
| DocumentPrincipal | DocumentPrincipal | application/pdf |
© 2011 Universitat Rovira i Virgili