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TITLE:
Optical Platform to Analyze a Model Drug-Loading and Releasing Profile Based on Nanoporous Anodic Alumina Gradient Index Filters - imarina:9187111

URV's Author/s:Acosta Capilla, Laura Karen / Ferré Borrull, José / Kapruwan, Pankaj / Marsal Garví, Luis Francisco
Author, as appears in the article.:Kapruwan, Pankaj; Acosta, Laura K; Ferre-Borrull, Josep; Marsal, Lluis F
Author's mail:pankaj.kapruwan1@estudiants.urv.cat
pankaj.kapruwan1@estudiants.urv.cat
laurakaren.acosta@urv.cat
josep.ferre@urv.cat
lluis.marsal@urv.cat
Author identifier:0000-0002-5210-5133
0000-0002-5976-1408
Journal publication year:2021
Publication Type:Journal Publications
APA:Kapruwan, Pankaj; Acosta, Laura K; Ferre-Borrull, Josep; Marsal, Lluis F (2021). Optical Platform to Analyze a Model Drug-Loading and Releasing Profile Based on Nanoporous Anodic Alumina Gradient Index Filters. Nanomaterials, 11(3), 1-16. DOI: 10.3390/nano11030730
Papper original source:Nanomaterials. 11 (3): 1-16
Abstract:In this work, a methodology that exploits the optical properties of the nanoporous anodic alumina gradient index filters (NAA-GIFs) has been developed and applied to evaluate in real time the release dynamics of a cargo molecule, acting as a model drug, filling the pores. NAA-GIFs with two photonic stopbands (PSBs) were prepared with one of its stop bands in the same absorption wavelength range of the cargo molecule, whereas the second stopband away from this absorption range. Numerical simulation and experiments confirm that the relative height of the high reflectance bands in the reflectance spectra of NAA-GIFs filled with the drug can be related to the relative amount of drug filling the pores. This property has been applied in a flow cell setup to measure in real-time the release dynamics of NAA-GIFs with the inner pore surface modified by layer-by-layer deposition of polyelectrolytes and loaded with the cargo molecule. The methodology developed in this work acts as a tool for the study of drug delivery from porous nanostructures.
Article's DOI:10.3390/nano11030730
Link to the original source:https://www.mdpi.com/2079-4991/11/3/730
Papper version:info:eu-repo/semantics/publishedVersion
licence for use:https://creativecommons.org/licenses/by/3.0/es/
Department:Enginyeria Electrònica, Elèctrica i Automàtica
Licence document URL:https://repositori.urv.cat/ca/proteccio-de-dades/
Thematic Areas:Physics, applied
Nanoscience & nanotechnology
Materials science, multidisciplinary
Materials science (miscellaneous)
Materials science (all)
General materials science
General chemical engineering
Engenharias ii
Chemistry, multidisciplinary
Chemical engineering (miscellaneous)
Chemical engineering (all)
Keywords:Rhodamine 6g
Polyelectrolytes
Photonic crystals
Optical monitoring
Nanoporous anodic alumina
Entity:Universitat Rovira i Virgili
Record's date:2024-10-12
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