URV's Author/s: | Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Díaz López, Andres / Paz Graniel, Indira del Socorro / Ruiz Garcia, Verónica / Salas Salvadó, Jorge |
Author, as appears in the article.: | Díaz-López, A; Paz-Graniel, I; Ruiz, V; Toledo, E; Becerra-Tomás, N; Corella, D; Castañer, O; Martínez, JA; Alonso-Gómez, AM; Wärnberg, J; Vioque, J; Romaguera, D; López-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, L; Bueno-Cavanillas, A; Tur, JA; Sánchez, VM; Pintó, X; Delgado-Rodríguez, M; Matía-Martín, P; Vidal, J; Vázquez, C; Daimiel, L; Villa, TF; Ros, E; Eguaras, S; Babio, N; Sorlí, JV; Goday, A; Abete, I; Sierra, LT; Barón-López, FJ; Torres-Collado, L; Morey, M; Garcia-Rios, A; Casas, R; Bernal-López, MR; Santos-Lozano, JM; Navarro, A; Gonzalez, JI; Zomeño, MD; Zulet, MA; Luna, JV; Ramallal, R; Fitó, M; Salas-Salvadó, J |
Author's mail: | veronica.ruiz@urv.cat indiradelsocorro.paz@urv.cat andres.diaz@urv.cat nerea.becerra@urv.cat veronica.ruiz@urv.cat indiradelsocorro.paz@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat |
Author identifier: | 0000-0002-3204-6877 0000-0002-7500-5629 0000-0002-4429-6507 0000-0002-3204-6877 0000-0003-2700-7459 0000-0003-3527-5277 |
Journal publication year: | 2021 |
Publication Type: | Journal Publications |
APA: | Díaz-López, A; Paz-Graniel, I; Ruiz, V; Toledo, E; Becerra-Tomás, N; Corella, D; Castañer, O; Martínez, JA; Alonso-Gómez, AM; Wärnberg, J; Vioque, J; (2021). Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome. Scientific Reports, 11(1), -. DOI: 10.1038/s41598-021-88028-7 |
Papper original source: | Scientific Reports. 11 (1): |
Abstract: | It remains unclear whether caffeinated beverages could have deleterious renal effects in elderly population with underlying comorbid conditions. We investigated the associations between coffee, tea, or caffeine intake and 1-year changes in glomerular filtration rate (eGFR) in a large Spanish cohort of overweight/obese elderly with metabolic syndrome (MetS). This prospective analysis includes 5851 overweight/obese adults (55-75 years) with MetS from the PREDIMED-Plus study. We assessed coffee, tea, and caffeine consumption from a validated food-frequency questionnaire and creatinine-based eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation. Multivariate-adjusted regression models were applied to test associations between baseline coffee, tea, or caffeine intake and 1-year eGFR changes. Caffeinated coffee (> 2 cups/day) and tea (at least 1 cup/day) drinkers had 0.88 and 0.93 mL/min/1.73 m(2) greater eGFR decrease respectively, compared to those with less than 1 cup/day of coffee consumption or non-tea drinkers. Furthermore, caffeinated coffee consumption of > 2 cups/day was associated with 1.19-fold increased risk of rapid eGFR decline > 3 mL/min/1.73 m(2) (95% CI 1.01-1.41). Similarly, individuals in the highest (median, 51.2 mg/day) tertile of caffeine intake had a 0.87 mL/min/1.73 m(2) greater eGFR decrease. Decaffeinated coffee was not associated with eGFR changes. In conclusion, higher consumption of caffeinated coffee, tea, and caffeine was associated with a greater 1-year eGFR decline in overweight/obese adults with MetS. |
Article's DOI: | 10.1038/s41598-021-88028-7 |
Link to the original source: | https://www.nature.com/articles/s41598-021-88028-7 |
Papper version: | info:eu-repo/semantics/publishedVersion |
licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
Department: | Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia |
Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
Thematic Areas: | Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física |
Keywords: | Tea Spain Risk Questionnaire Pathophysiology Outcomes Middle aged Metabolic syndrome x Metabolic syndrome Male Kidney Hyperfiltration Humans Human Health Glomerulus filtration rate Glomerular-filtration-rate Glomerular filtration rate Female Drinking behavior Cohort studies Cohort analysis Coffee consumption Coffee Cardiovascular-diseases Caffeine Association Aged |
Entity: | Universitat Rovira i Virgili |
Record's date: | 2024-07-27 |
Description: | It remains unclear whether caffeinated beverages could have deleterious renal effects in elderly population with underlying comorbid conditions. We investigated the associations between coffee, tea, or caffeine intake and 1-year changes in glomerular filtration rate (eGFR) in a large Spanish cohort of overweight/obese elderly with metabolic syndrome (MetS). This prospective analysis includes 5851 overweight/obese adults (55-75 years) with MetS from the PREDIMED-Plus study. We assessed coffee, tea, and caffeine consumption from a validated food-frequency questionnaire and creatinine-based eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation. Multivariate-adjusted regression models were applied to test associations between baseline coffee, tea, or caffeine intake and 1-year eGFR changes. Caffeinated coffee (> 2 cups/day) and tea (at least 1 cup/day) drinkers had 0.88 and 0.93 mL/min/1.73 m(2) greater eGFR decrease respectively, compared to those with less than 1 cup/day of coffee consumption or non-tea drinkers. Furthermore, caffeinated coffee consumption of > 2 cups/day was associated with 1.19-fold increased risk of rapid eGFR decline > 3 mL/min/1.73 m(2) (95% CI 1.01-1.41). Similarly, individuals in the highest (median, 51.2 mg/day) tertile of caffeine intake had a 0.87 mL/min/1.73 m(2) greater eGFR decrease. Decaffeinated coffee was not associated with eGFR changes. In conclusion, higher consumption of caffeinated coffee, tea, and caffeine was associated with a greater 1-year eGFR decline in overweight/obese adults with MetS. |
Type: | Journal Publications |
Contributor: | Universitat Rovira i Virgili |
Títol: | Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome |
Subject: | Multidisciplinary,Multidisciplinary Sciences Tea Spain Risk Questionnaire Pathophysiology Outcomes Middle aged Metabolic syndrome x Metabolic syndrome Male Kidney Hyperfiltration Humans Human Health Glomerulus filtration rate Glomerular-filtration-rate Glomerular filtration rate Female Drinking behavior Cohort studies Cohort analysis Coffee consumption Coffee Cardiovascular-diseases Caffeine Association Aged Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física |
Date: | 2021 |
Creator: | Díaz-López, A Paz-Graniel, I Ruiz, V Toledo, E Becerra-Tomás, N Corella, D Castañer, O Martínez, JA Alonso-Gómez, AM Wärnberg, J Vioque, J Romaguera, D López-Miranda, J Estruch, R Tinahones, FJ Lapetra, J Serra-Majem, L Bueno-Cavanillas, A Tur, JA Sánchez, VM Pintó, X Delgado-Rodríguez, M Matía-Martín, P Vidal, J Vázquez, C Daimiel, L Villa, TF Ros, E Eguaras, S Babio, N Sorlí, JV Goday, A Abete, I Sierra, LT Barón-López, FJ Torres-Collado, L Morey, M Garcia-Rios, A Casas, R Bernal-López, MR Santos-Lozano, JM Navarro, A Gonzalez, JI Zomeño, MD Zulet, MA Luna, JV Ramallal, R Fitó, M Salas-Salvadó, J |
Rights: | info:eu-repo/semantics/openAccess |
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