Repositori institucional URV
| URV's Author/s: | Arola Arnal, Anna / Arreaza Gil, Verónica / Ávila Román, Francisco Javier / Escobar Martínez, Ivan / Muguerza Marquínez, Maria Begoña / Suárez Recio, Manuel / Torres Fuentes, Cristina |
| Author, as appears in the article.: | Arreaza-Gil, V; Avila-Román, J; Escobar-Martínez, I; Muguerza, B; Suárez, M; Arola-Arnal, A; Torres-Fuentes, C |
| Author's mail: | franciscojavier.avila@urv.cat ivan.escobar@estudiants.urv.cat veronica.arreaza@estudiants.urv.cat veronica.arreaza@estudiants.urv.cat manuel.suarez@urv.cat anna.arola@urv.cat begona.muguerza@urv.cat cristina.torres@urv.cat |
| Author identifier: | 0000-0001-9766-8178 0000-0002-8301-2095 0000-0002-8301-2095 0000-0003-0122-8253 0000-0001-6529-1345 0000-0001-7384-8588 0000-0002-2917-6910 |
| Journal publication year: | 2023 |
| Publication Type: | Journal Publications |
| APA: | Arreaza-Gil, V; Avila-Román, J; Escobar-Martínez, I; Muguerza, B; Suárez, M; Arola-Arnal, A; Torres-Fuentes, C (2023). Photoperiod Conditions Modulate Serum Oxylipins Levels in Healthy and Obese Rats: Impact of Proanthocyanidins and Gut Microbiota. Nutrients, 15(3), -. DOI: 10.3390/nu15030707 |
| Papper original source: | Nutrients. 15 (3): |
| Abstract: | Seasonal rhythms are emerging as a key factor influencing gut microbiota and bioactive compounds functionality as well as several physiological processes such as inflammation. In this regard, their impact on the modulation of oxylipins (OXLs), which are important lipid mediators of inflammatory processes, has not been investigated yet. Hence, we aimed to investigate the effects of photoperiods on OXLs metabolites in healthy and obesogenic conditions. Moreover, we evaluated if the impact of proanthocyanidins and gut microbiota on OXLs metabolism is influenced by photoperiod in obesity. To this purpose, Fischer 344 rats were housed under different photoperiod conditions (L6: 6 h light, L12: 12 h light or L18:18 h light) and fed either a standard chow diet (STD) or a cafeteria diet (CAF) for 9 weeks. During the last 4 weeks, obese rats were daily administered with an antibiotic cocktail (ABX), an oral dose of a grape seed proanthocyanidin extract (GSPE), or with their combination. CAF feeding and ABX treatment affected OXLs in a photoperiod dependent-manner. GSPE significantly altered prostaglandin E2 (PGE2) levels, only under L6 and mitigated ABX-mediated effects only under L18. In conclusion, photoperiods affect OXLs levels influenced by gut microbiota. This is the first time that the effects of photoperiod on OXLs metabolites have been demonstrated. |
| Article's DOI: | 10.3390/nu15030707 |
| Link to the original source: | https://www.mdpi.com/2072-6643/15/3/707 |
| Papper version: | info:eu-repo/semantics/publishedVersion |
| licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
| Department: | Bioquímica i Biotecnologia |
| Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Thematic Areas: | Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología |
| Keywords: | Seasonal-variation Resolvins Obesity Gspe Cafeteria diet Biological rhythms weight resolvins profiles obesity metabolism mediators inflammation gspe clock cafeteria diet acid |
| Entity: | Universitat Rovira i Virgili |
| Record's date: | 2024-08-03 |
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