Repositori institucional URV
| URV's Author/s: | Alkhoury, Nadine / Babio Sánchez, Nancy Elvira / García Gavilán, Jesús Francisco / Ni, Jiaqi / Nishi, Stephanie Kimiko / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge / Valle Hita, Cristina |
| Author, as appears in the article.: | Nishi, Stephanie K; Paz-Graniel, Indira; Ni, Jiaqi; Valle-Hita, Cristina; Khoury, Nadine; Garcia-Gavilan, Jesus F; Babio, Nancy; Salas-Salvado, Jordi |
| Author's mail: | stephanie.nishi@urv.cat nadine.alkhoury@urv.cat jiaqi.ni@urv.cat jesusfrancisco.garcia@urv.cat cristina.valle@alumni.urv.cat indiradelsocorro.paz@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat |
| Author identifier: | 0000-0001-5625-0373 0000-0002-3707-5255 0000-0002-3204-6877 0000-0003-2700-7459 0000-0003-3527-5277 |
| Journal publication year: | 2025-05-01 |
| Publication Type: | Journal Publications |
| APA: | Nishi, Stephanie K; Paz-Graniel, Indira; Ni, Jiaqi; Valle-Hita, Cristina; Khoury, Nadine; Garcia-Gavilan, Jesus F; Babio, Nancy; Salas-Salvado, Jordi (2025). Effect of nut consumption on blood lipids: An updated systematic review and meta-analysis of randomized controlled trials. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 35(5), 103771-. DOI: 10.1016/j.numecd.2024.10.009 |
| Paper original source: | NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 35 (5): 103771- |
| Abstract: | Aims: Nuts are nutrient-dense foods touted for their health-promoting effects, especially regarding cardiovascular health, yet inconsistencies in the literature remain in relation to their effect on blood lipids. Hence, a systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to determine the effect of nut intake on blood lipids. Data synthesis: MEDLINE-PubMed and Cochrane databases were searched. 113 unique trials met eligibility criteria (n = 8060 adults with various health status) assessing the effect of a median daily dose of 45.5 g/d of nuts compared to a non-nut control on blood lipid outcomes met inclusion criteria. Overall, nut consumption resulted in moderate reductions in total cholesterol (mean difference, -0.14 mmol/L [95 % confidence interval, -0.18 to -0.10 mmol/L]) and LDL-C (-0.12 mmol/L [-0.14 to -0.09 mmol/L]), with small reductions in triglycerides (-0.05 mmol/L [-0.07 to -0.03 mmol/L]), TC:HDL-C (-0.11 [-0.16 to -0.06]), LDL-C:HDL-C (-0.19 [-0.24 to -0.12]), and apolipoprotein B (-0.04 g/L [-0.06 to -0.02 g/L]). There was no significant impact on HDLcholesterol or other assessed measures. Certainty of evidence was high for apolipoprotein A, and generally moderate/low for all other outcomes. Sensitivity analysis did not change the evidence on the main outcomes. Significant effect modifications in subgroup analysis were shown for most of the lipid parameters assessed. None of these subgroup effects altered the evidence of heterogeneity for any primary outcome. Conclusions: Current evidence provides a good indication that consuming nuts may advantageously affect blood lipids in adults with a mix of health status. Prospero registration: PROSPERO identifier, CRD42022358688. |
| Article's DOI: | 10.1016/j.numecd.2024.10.009 |
| Link to the original source: | https://www.nmcd-journal.com/article/S0939-4753(24)00390-9/fulltext |
| Paper version: | info:eu-repo/semantics/publishedVersion |
| licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
| Department: | Bioquímica i Biotecnologia |
| Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Thematic Areas: | Nutrition and dietetics Nutrition & dietetics Medicine (miscellaneous) Interdisciplinar General medicine Endocrinology, diabetes and metabolism Endocrinology & metabolism Educação física Cardiology and cardiovascular medicine Cardiac & cardiovascular systems Biotecnología |
| Keywords: | Zero hunger Society guidelines Randomized controlled trials as topic Pistachio nuts Peanuts Nuts Nutritive value Monounsaturated fat Moderate walnut consumption Middle aged Metabolic syndrome Male Lipids Ldl-c Humans Female Enriched diet Endothelial function Dyslipidemias Dyslipidemia Diet, healthy Cholesterol Cardiovascular risk-factors Cardiovascular health Cardiovascular healt Body-compositio Blood lipids Biomarkers Almond consumption Aged Adult |
| Entity: | Universitat Rovira i Virgili |
| Record's date: | 2026-08-01 |
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