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TITLE:
Sex differences in the effect of childhood trauma on the clinical expression of early psychosis - PC:1515

URV's Author/s:GUTIÉRREZ ZOTES, JOSÉ ALFONSO; Myriam Garcia; Itziar Montalvo; Marta Creus; Ángel Cabezas; Montse Solé; Maria José Algora; Irene Moreno; Javier Labad
Author, as appears in the article.:Alfonso Gutiérrez-Zotes; Myriam Garcia; Itziar Montalvo; Marta Creus; Ángel Cabezas; Montse Solé; Maria José Algora; Irene Moreno; Javier Labad
Author identifier:N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D
Journal publication year:2016
Publication Type:Article
ISSN:0010-440X
Abstract:Childhood trauma, a risk factor of psychosis, is associated the clinical expression of the illness (greater severity of psychotic symptoms; poorer cognitive performance). We aimed to explore whether there are sex differences in this relationship. We studied 79 individuals with a psychotic disorder (PD) with < 3 years of illness and 59 healthy subjects (HS). All participants were administered the MATRICS Cognitive Consensus Cognitive Battery (MCCB) to assess cognition. Depressive, positive and negative psychotic symptoms, and global functioning were also assessed. History of childhood trauma was assessed using the Childhood Trauma Questionnaire (CTQ). Patients reported a greater history of childhood trauma on all CTQ domains (emotional, physical and sexual abuse, and physical and emotional neglect). A poorer cognitive performance was also observed in PD when compared to HS. No sex differences were found in the CTQ scores. In the relationship between childhood trauma and psychopathological symptoms, significant correlations were found between CTQ scores and positive and negative psychotic symptoms, depressive symptoms and poorer functionality, but only in women. Childhood trauma was associated with poorer social cognition in both men and women. Of all CTQ dimensions, emotional neglect and physical neglect were more clearly associated with a more severe psychopathological and cognitive profile. Our results suggest that childhood trauma, particularly emotional and physical neglect, is associated with the clinical expression of psychosis and that there are sex differences in this relationship.
Article's DOI:10.1016/j.comppsych.2016.04.004
Link to the original source:https://www.sciencedirect.com/science/article/abs/pii/S0010440X15302480
Papper version:info:eu-repo/semantics/acceptedVersion
licence for use:https://creativecommons.org/licenses/by/3.0/es/
Department:Medicina i Cirurgia
Research group:Grup d'Investigació en Psiquiatria
Licence document URL:https://repositori.urv.cat/ca/proteccio-de-dades/
Thematic Areas:Health sciences
Keywords:sex differences
childhood trauma
Entity:Universitat Rovira i Virgili
Record's date:2016-05-10
First page:86
Last page:96
Journal volume:68
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