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Extra virgin olive oil consumption reduces the risk of osteoporotic fractures in the PREDIMED trial - imarina:2943202

Autor/s de la URV:Bulló Bonet, Mònica / Salas Salvadó, Jorge
Autor segons l'article:García-Gavilán J; Bulló M; Canudas S; Martínez-González M; Estruch R; Giardina S; Fitó M; Corella D; Ros E; Salas-Salvadó J
Adreça de correu electrònic de l'autor:monica.bullo@urv.cat
jordi.salas@urv.cat
Identificador de l'autor:0000-0002-0218-7046
0000-0003-2700-7459
Any de publicació de la revista:2018
Tipus de publicació:Journal Publications
ISSN:02615614
Referència de l'ítem segons les normes APA:García-Gavilán J; Bulló M; Canudas S; Martínez-González M; Estruch R; Giardina S; Fitó M; Corella D; Ros E; Salas-Salvadó J (2018). Extra virgin olive oil consumption reduces the risk of osteoporotic fractures in the PREDIMED trial. Clinical Nutrition, 37(1), 329-335. DOI: 10.1016/j.clnu.2016.12.030
Referència a l'article segons font original:Clinical Nutrition. 37 (1): 329-335
Resum:The incidence of osteoporotic fractures is lower in countries in the Mediterranean basin. Virgin olive oil, a key component of the Mediterranean Diet (MDiet), with recognised beneficial effects on metabolism and cardiovascular health, may decrease the risk of osteoporotic fractures. The aim to this study was to explore the effect of chronic consumption of total olive oil and its varieties on the risk of osteoporosis-related fractures in a middle-aged and elderly Mediterranean population.We included all participants (n = 870) recruited in the Reus (Spain) centre of the PREvención con DIeta MEDiterránea (PREDIMED) trial. Individuals, aged 55-80 years at high cardiovascular risk, were randomized to a MedDiet supplemented with extra-virgin olive oil, a MedDiet supplemented with nuts, or a low-fat diet. The present analysis was an observational cohort study nested in the trial. A validated food frequency questionnaire was used to assess dietary habits and olive oil consumption. Information on total osteoporotic fractures was obtained from a systematic review of medical records. The association between yearly repeated measurements of olive oil consumption and fracture risk was assessed by multivariate Cox proportional hazards.We documented 114 incident cases of osteoporosis-related fractures during a median follow-up of 8.9 years. Treatment allocation had no effect on fracture risk. Participants in the highest tertile of extra-virgin olive oil consumption had a 51% lower risk of fractures (HR:0.49; 95% CI:0.29-0.81. P for trend = 0.004) compared to those in the lowest tertile after adjusting for potential confounders. Total and common olive oil consumption was not associated with fracture risk.Higher consumption of extra-virgin olive oil is associated with a lower risk of osteoporosis-related fractures in middle-aged and elderly Mediterranean population at high cardiovascular risk.Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
DOI de l'article:10.1016/j.clnu.2016.12.030
Enllaç font original:https://www.clinicalnutritionjournal.com/article/S0261-5614(17)30006-7/fulltext
Versió de l'article dipositat:info:eu-repo/semantics/acceptedVersion
Accès a la llicència d'ús:https://creativecommons.org/licenses/by/3.0/es/
Departament:Bioquímica i Biotecnologia
URL Document de llicència:http://repositori.urv.cat/ca/proteccio-de-dades/
Àrees temàtiques:Saúde coletiva
Química
Odontología
Nutrition and dietetics
Nutrition & dietetics
Nutrição
Medicina iii
Medicina ii
Medicina i
Interdisciplinar
General medicine
Farmacia
Engenharias iv
Enfermagem
Educação física
Critical care and intensive care medicine
Ciências biológicas iii
Ciências biológicas ii
Ciências biológicas i
Ciência de alimentos
Biotecnología
Paraules clau:Prevention
Osteoporotic fractures
Olive oil
Aging
osteoporotic fractures
olive oil
aging
Entitat:Universitat Rovira i Virgili
Data d'alta del registre:2024-07-20
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