Repositori institucional URV
| URV's Author/s: | SALAS SALVADÓ, JORGE; Maria Jesus Jiménez Expósito; Pilar Garcia Lorda; Carlos Alfonso Villaverde; Carmen M de Vírgala; Rosa Solà; Lluis Masana; Victoria Arija; Vicente Izquierdo |
| Author, as appears in the article.: | Jordi Salas Salvado; Maria Jesus Jiménez Expósito; Pilar Garcia Lorda; Carlos Alfonso Villaverde; Carmen M de Vírgala; Rosa Solà; Lluis Masana; Victoria Arija; Vicente Izquierdo |
| Author identifier: | orcid.org/0000-0003-2700-7459; N/D; orcid.org/0000-0001-8938-7229; N/D; N/D; orcid.org/0000-0002-8359-235X; orcid.org/0000-0002-0789-4954; orcid.org/0000-0002-1758-0975; N/D |
| Journal publication year: | 1998 |
| Publication Type: | Article |
| ISSN: | 0269-9370 |
| Abstract: | OBJECTIVE:
To assess the influence of malabsorption on nutritional status and energy expenditure in patients at different stages of HIV infection.
DESIGN AND METHODS:
Fifty HIV patients were classified into three groups: Group 1, HIV asymptomatic patients (n=17); Group 2, AIDS without opportunistic infection (n=16); Group 3, AIDS patients with active infection (n=17). Clinically-healthy subjects (n=19) were used as controls. Parameters measured were: anthropometry, body composition by tetrapolar bioelectrical impedance; resting energy expenditure (REE) by open-circuit indirect calorimetry; malabsoption by D-xylose absorption and triolein breath tests.
RESULTS:
Malabsorption (defined as abnormality of xylose and/or fat absorption test) was found in 34 (68%) of patients: 9 (53%) Group 1; 11 (69%) Group 2; 14 (82%) Group 3. Twenty-seven (54%) had sugar malabsorption and 21 (42%) fat malabsorption. A significant relationship was observed between malabsorption and weight loss. REE measured was significantly lower in malabsorptive patients than in non-malabsorptive patients and controls (6006.3+/-846.5 versus 6443.4 + 985.5 versus 6802.1+/-862.7 kJ/day, respectively; P < 0.05). The REE adjusted for fat-free mass was lower in malabsorptive than in non-malabsorptive patients and slightly higher than in controls, although the differences were not statistically significant.
CONCLUSIONS:
The results suggest that malabsorption is a frequent feature in HIV infection and is related to the HIV-related weight loss. Hypermetabolism is not a constant phenomenon in HIV infection since, in the presence of malabsorption, our patients show an appropriate metabolic response with a compensatory decrease in REE. |
| Papper version: | info:eu-repo/semantics/publishedVersion |
| licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
| Department: | Bioquímica i Biotecnologia |
| Research group: | Alimentació, Nutrició, Creixement i Salut Mental |
| Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Thematic Areas: | Biochemistry and technology |
| Keywords: | HIV infection aids malabsorption |
| Entity: | Universitat Rovira i Virgili |
| Record's date: | 2016-06-08 |
| First page: | 1965 |
| Last page: | 1972 |
| Journal volume: | 12 |
| Search your record at: |     |
| File | Description | Format | |
|---|---|---|---|
| DocumentPrincipal | DocumentPrincipal | application/pdf |
© 2011 Universitat Rovira i Virgili