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Dairy product consumption and risk of colorectal cancer in an older Mediterranean population at high cardiovascular risk. - imarina:3423196

Autor/s de la URV:Babio Sánchez, Nancy Elvira / Barrubés Piñol, Laura / Basora Gallisà, Josep / MENA SÁNCHEZ, GUILLERMO / Salas Huetos, Albert / Salas Salvadó, Jorge
Autor segons l'article:Barrubes, Laura; Babio, Nancy; Mena-Sanchez, Guillermo; Toledo, Estefania; Ramirez-Sabio, Judith B; Estruch, Ramon; Ros, Emilio; Fito, Montserrat; Aros, Fernando; Fiol, Miquel; Manuel Santos-Lozano, Jose; Serra-Majem, Lluis; Pinto, Xavier; Angel Martinez-Gonzalez, Miguel; Vicente Sorli, Jose; Basora, Josep; Salas-Salvado, Jordi
Adreça de correu electrònic de l'autor:josep.basora@urv.cat
josep.basora@urv.cat
albert.salas@urv.cat
albert.salas@urv.cat
josep.basora@urv.cat
jordi.salas@urv.cat
jordi.salas@urv.cat
nancy.babio@urv.cat
nancy.babio@urv.cat
Identificador de l'autor:0000-0001-5914-6862
0000-0001-5914-6862
0000-0003-2700-7459
0000-0003-2700-7459
0000-0003-3527-5277
0000-0003-3527-5277
Any de publicació de la revista:2018-09-15
Tipus de publicació:Journal Publications
ISSN:00207136
Referència de l'ítem segons les normes APA:Barrubes, Laura; Babio, Nancy; Mena-Sanchez, Guillermo; Toledo, Estefania; Ramirez-Sabio, Judith B; Estruch, Ramon; Ros, Emilio; Fito, Montserrat; Aro (2018). Dairy product consumption and risk of colorectal cancer in an older Mediterranean population at high cardiovascular risk.. INTERNATIONAL JOURNAL OF CANCER, 143(6), 1356-1366. DOI: 10.1002/ijc.31540
Referència a l'article segons font original:INTERNATIONAL JOURNAL OF CANCER. 143 (6): 1356-1366
Resum:© 2018 UICC. Prospective studies have reported an inverse association between the consumption of total dairy products and milk and the risk of colorectal cancer (CRC). Nonetheless, there is little and inconsistent evidence regarding subtypes of dairy product and CRC risk. We assessed the associations between the consumption of total dairy products, their different subtypes and CRC risk in older Mediterranean individuals at high cardiovascular risk. We analyzed data from 7,216 men and women (55-80 years) without CRC at baseline from the PREvención con DIeta MEDiterránea study. Individuals were recruited between 2003 and 2009 and followed up until December 2012. At baseline and yearly thereafter, consumption of total and specific dairy products was assessed using a validated 137-item food-frequency questionnaire. Cox proportional hazards ratios (HRs) of CRC incidence were estimated for tertiles of mean consumption of dairy products during the follow-up. During a median [interquartile range] follow-up of 6.0 [4.4-7.3] years, we documented 101 incident CRC cases. In the multivariable-adjusted models, HRs and 95% confidence intervals (CIs) of CRC for the comparison of extreme tertiles of total dairy product and low-fat milk consumption were 0.55 (95% CI: 0.31-0.99; p-trend=0.037) and 0.54 (95% CI: 0.32-0.92; p-trend=0.022), respectively. No significant associations with other dairy products (whole-fat and low-fat dairy products; total, low-fat and whole-fat yogurt; cheese; total, low-fat and whole-fat milk; concentrated full-fat dairy products, sugar-enriched dairy products and fermented dairy products) were found. A high consumption of total dairy products and low-fat milk was significantly associated with a reduced CRC risk.
DOI de l'article:10.1002/ijc.31540
Enllaç font original:https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijc.31540
Versió de l'article dipositat:info:eu-repo/semantics/acceptedVersion
Accès a la llicència d'ús:https://creativecommons.org/licenses/by/3.0/es/
Departament:Bioquímica i Biotecnologia
URL Document de llicència:https://repositori.urv.cat/ca/proteccio-de-dades/
Àrees temàtiques:Oncology
General medicine
Ciências biológicas i
Cancer research
Biotecnología
Paraules clau:Risk factors
Prospective studies
Prognosis
Predimed study
Milk
Middle aged
Mediterranean region
Mediterranean diet
Male
Incidence
Humans
Follow-up studies
Female
Dairy products
Colorectal neoplasms
Colorectal cancer
Case-control studies
Cardiovascular diseases
Aged, 80 and over
Aged
predimed study
mediterranean diet
dairy products
colorectal cancer
Entitat:Universitat Rovira i Virgili
Data d'alta del registre:2026-05-09
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