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Pandemic and post-pandemic Influenza A (H1N1) infection in critically ill patients - imarina:34835

Autor/s de la URV:Cabre Vila, Juan Jose / Rodríguez Oviedo, Alejandro Hugo
Autor segons l'article:Martin-Loeches I, Díaz E, Vidaur L, Torres A, Laborda C, Granada R, Bonastre J, Martín M, Insausti J, Arenzana A, Guerrero JE, Navarrete I, Bermejo-Martin J, Suarez D, Rodriguez A, H1N1 SEMICYUC/REIPI/CIBERES Working group
Adreça de correu electrònic de l'autor:juanjose.cabre@urv.cat
alejandrohugo.rodriguez@urv.cat
Identificador de l'autor:0000-0003-1082-6861
0000-0001-8828-5984
Any de publicació de la revista:2011
Tipus de publicació:Journal Publications
ISSN:1466609X
Referència de l'ítem segons les normes APA:Martin-Loeches I, Díaz E, Vidaur L, Torres A, Laborda C, Granada R, Bonastre J, Martín M, Insausti J, Arenzana A, Guerrero JE, Navarrete I, Bermejo-Ma (2011). Pandemic and post-pandemic Influenza A (H1N1) infection in critically ill patients. Critical Care, 15(6), R286-R286. DOI: 10.1186/cc10573
Referència a l'article segons font original:Critical Care. 15 (6): R286-R286
Resum:There is a vast amount of information published regarding the impact of 2009 pandemic Influenza A (pH1N1) virus infection. However, a comparison of risk factors and outcome during the 2010-2011 post-pandemic period has not been described.A prospective, observational, multi-center study was carried out to evaluate the clinical characteristics and demographics of patients with positive RT-PCR for H1N1 admitted to 148 Spanish intensive care units (ICUs). Data were obtained from the 2009 pandemic and compared to the 2010-2011 post-pandemic period.Nine hundred and ninety-seven patients with confirmed An/H1N1 infection were included. Six hundred and forty-eight patients affected by 2009 (pH1N1) virus infection and 349 patients affected by the post-pandemic Influenza (H1N1)v infection period were analyzed. Patients during the post-pandemic period were older, had more chronic comorbid conditions and presented with higher severity scores (Acute Physiology And Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA)) on ICU admission. Patients from the post-pandemic Influenza (H1N1)v infection period received empiric antiviral treatment less frequently and with delayed administration. Mortality was significantly higher in the post-pandemic period. Multivariate analysis confirmed that haematological disease, invasive mechanical ventilation and continuous renal replacement therapy were factors independently associated with worse outcome in the two periods. HIV was the only new variable independently associated with higher ICU mortality during the post-pandemic Influenza (H1N1)v infection period.Patients from the post-pandemic Influenza (H1N1)v infection period had an unexpectedly higher mortality rate and showed a trend towards affecting a more vulnerable population, in keeping with more typical seasonal viral infection.
DOI de l'article:10.1186/cc10573
Enllaç font original:https://ccforum.biomedcentral.com/articles/10.1186/cc10573
Versió de l'article dipositat:info:eu-repo/semantics/publishedVersion
Accès a la llicència d'ús:https://creativecommons.org/licenses/by/3.0/es/
Departament:Medicina i Cirurgia
URL Document de llicència:https://repositori.urv.cat/ca/proteccio-de-dades/
Àrees temàtiques:Saúde coletiva
Nutrição
Medicina veterinaria
Medicina iii
Medicina ii
Medicina i
Interdisciplinar
Farmacia
Engenharias iv
Enfermagem
Educação física
Critical care medicine
Critical care and intensive care medicine
Ciências biológicas iii
Ciências biológicas ii
Ciências biológicas i
Ciência de alimentos
Biotecnología
Paraules clau:Good health and well-being
Entitat:Universitat Rovira i Virgili
Data d'alta del registre:2024-11-16
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