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Association study of monoamine oxidase-A gene promoter polymorphism (MAOA-uVNTR) with self-reported anxiety and other psychopathological symptoms in a community sample of early adolescents - imarina:3642034

Autor/es de la URV:Aparicio Llopis, Estefania / Arija Val, Maria Victoria / Canals Sans, Josefa / Voltas Moreso, Núria
Autor según el artículo:Voltas N, Aparicio E, Arija V, Canals J.
Direcció de correo del autor:nuria.voltas@urv.cat
josefa.canals@urv.cat
victoria.arija@urv.cat
Identificador del autor:0000-0001-8855-0282
0000-0002-6209-9558
0000-0002-1758-0975
Año de publicación de la revista:2015
Tipo de publicación:Journal Publications
Referencia de l'ítem segons les normes APA:Voltas N, Aparicio E, Arija V, Canals J. (2015). Association study of monoamine oxidase-A gene promoter polymorphism (MAOA-uVNTR) with self-reported anxiety and other psychopathological symptoms in a community sample of early adolescents. Journal Of Anxiety Disorders, 31(), 65-72. DOI: 10.1016/j.janxdis.2015.02.004
Referencia al articulo segun fuente origial:Journal Of Anxiety Disorders. 31 65-72
Resumen:The polymorphism upstream of the gene for monoamine oxidase A (MAOA-uVNTR) is reported to be an important enzyme involved in human physiology and behavior. With a sample of 228 early-adolescents from a community sample (143 girls) and adjusting for environmental variables, we examined the influence of MAOA-uVNTR alleles on the scores obtained in the Screen for Childhood Anxiety and Related Emotional Disorders and in the Child Symptom Inventory-4. Our results showed that girls with the high-activity MAOA allele had higher scores for generalized and total anxiety than their low-activity peers, whereas boys with the low-activity allele had higher social phobia scores than boys with the high-activity allele. Results for conduct disorder symptoms did not show a significant relationship between the MAOA alleles and the presence of these symptoms. Our findings support a possible association, depending on gender, between the MAOA-uVNTR polymorphism and psychopathological disorders such as anxiety, which affects high rates of children and adolescents.
DOI del artículo:10.1016/j.janxdis.2015.02.004
Enlace a la fuente original:https://www.sciencedirect.com/science/article/abs/pii/S0887618515000274?via%3Dihub
Versión del articulo depositado:info:eu-repo/semantics/submittedVersion
Acceso a la licencia de uso:https://creativecommons.org/licenses/by/3.0/es/
Departamento:Ciències Mèdiques Bàsiques
Psicologia
URL Documento de licencia:https://repositori.urv.cat/ca/proteccio-de-dades/
Áreas temáticas:Saúde coletiva
Psychology, clinical
Psychology
Psychiatry and mental health
Psychiatry
Psicología
Nutrição
Medicina ii
Medicina i
General medicine
Educação física
Clinical psychology
Ciencias sociales
Ciências biológicas ii
Palabras clave:Psychopathology
Maoa-uvntr
Gender
Anxiety
Adolescents
maoa-uvntr
gender
anxiety
adolescents
Entidad:Universitat Rovira i Virgili
Fecha de alta del registro:2024-09-07
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