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Prognostic implications of troponin I elevation in emergency department patients with tachyarrhythmia - imarina:5873999

Autor/es de la URV:Bardají Ruiz, Alfredo / Bonet Pineda, Gil / Carrasquer Cucarella, Ana Maria
Autor según el artículo:González-Del-Hoyo, M; Cediel, G; Carrasquer, A; Bonet, G; Vásquez-Nuñez, K; Boqué, C; Alí, S; Bardají, A
Direcció de correo del autor:gil.bonet@urv.cat
gil.bonet@urv.cat
anamaria.carrasquer@urv.cat
anamaria.carrasquer@urv.cat
anamaria.carrasquer@urv.cat
alfredo.bardaji@urv.cat
alfredo.bardaji@urv.cat
Identificador del autor:0000-0003-1900-6974
0000-0003-1900-6974
Año de publicación de la revista:2019-05-01
Tipo de publicación:Journal Publications
ISSN:01609289
Referencia de l'ítem segons les normes APA:González-Del-Hoyo, M; Cediel, G; Carrasquer, A; Bonet, G; Vásquez-Nuñez, K; Boqué, C; Alí, S; Bardají, A (2019). Prognostic implications of troponin I elevation in emergency department patients with tachyarrhythmia. Clinical Cardiology, 42(5), 546-552. DOI: 10.1002/clc.23175
Referencia al articulo segun fuente origial:Clinical Cardiology. 42 (5): 546-552
Resumen:© 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. Background: Tachyarrhythmias are very common in emergency medicine, and little is known about the long-term prognostic implications of troponin I levels in these patients. Hypothesis: This study aimed to investigate the correlation of cardiac troponin I (cTnI) levels and long-term prognosis in patients admitted to the emergency department (ED) with a primary diagnosis of tachyarrhythmia. Methods: A retrospective cohort study was conducted between January 2012 and December 2013, enrolling patients admitted to the ED with a primary diagnosis of tachyarrhythmia and having documented cTnI measurements. Clinical characteristics and 5-year all-cause mortality were analyzed. Results: Of a total of 222 subjects with a primary diagnosis of tachyarrhythmia, 73 patients had elevated levels of cTnI (32.9%). Patients with elevated cTnI levels were older and presented significantly more cardiovascular risk factors. At the 5-year follow-up, mortality was higher among patients with elevated cTnI levels (log-rank test P < 0.001). In the multivariable Cox regression analysis, elevated cTnI was an independent predictor of all-cause death (hazard ratio, 1.95, 95% confidence interval: 1.08-3.50, P = 0.026), in addition to age and prior heart failure. Conclusion: Patients admitted to the ED with a primary diagnosis of tachyarrhythmia and high cTnI levels have higher long-term mortality rates than patients with low cTnI levels. cTnI is thus a biomarker with predictive capacity for mortality in late follow-up, conferring utility in the risk stratification of this population.
DOI del artículo:10.1002/clc.23175
Enlace a la fuente original:https://onlinelibrary.wiley.com/doi/full/10.1002/clc.23175
Versión del articulo depositado:info:eu-repo/semantics/publishedVersion
Acceso a la licencia de uso:https://creativecommons.org/licenses/by/3.0/es/
Departamento:Medicina i Cirurgia
URL Documento de licencia:https://repositori.urv.cat/ca/proteccio-de-dades/
Áreas temáticas:Saúde coletiva
Medicine (miscellaneous)
General medicine
Enfermagem
Ciências biológicas ii
Cardiology and cardiovascular medicine
Cardiac & cardiovascular systems
Palabras clave:Up-regulation
Troponin i
Time factors
Risk factors
Risk assessment
Retrospective studies
Prognosis
Predictive value of tests
Paroxysmal supraventricular tachycardia
Outcomes
Myocardial-infarction
Mortality
Middle aged
Management
Male
Humans
Female
Emergency service, hospital
Emergency department
Chest-pain
Cardiac troponin
Biomarkers
Association
Assay
Arrhythmias, cardiac
Arrhythmia
Aged, 80 and over
Aged
cardiac troponin
arrhythmia
Entidad:Universitat Rovira i Virgili
Fecha de alta del registro:2026-05-09
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