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Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study - imarina:6395497

Autor/s de la URV:Babio Sánchez, Nancy Elvira / Barrubés Piñol, Laura / Salas Salvadó, Jorge
Autor segons l'article:Barrubés L, Babio N, Hernández-Alonso P, Toledo E, Ramírez Sabio JB, Estruch R, Ros E, Fitó M, Alonso-Gómez AM, Fiol M, Lapetra J, Serra-Majem L, Pintó X, Ruiz-Canela M, Corella D, Castañer O, Macías-González M, Salas-Salvadó J
Adreça de correu electrònic de l'autor:jordi.salas@urv.cat
nancy.babio@urv.cat
Identificador de l'autor:0000-0003-2700-7459
0000-0003-3527-5277
Any de publicació de la revista:2020
Tipus de publicació:Journal Publications
ISSN:20770383
Referència de l'ítem segons les normes APA:Barrubés L, Babio N, Hernández-Alonso P, Toledo E, Ramírez Sabio JB, Estruch R, Ros E, Fitó M, Alonso-Gómez AM, Fiol M, Lapetra J, Serra-Majem L, Pint (2020). Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study. Journal Of Clinical Medicine, 9(4), -. DOI: 10.3390/jcm9041215
Referència a l'article segons font original:Journal Of Clinical Medicine. 9 (4):
Resum:Limited longitudinal studies have been conducted to evaluate colorectal cancer (CRC) incidence based on the updated 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations or other global lifestyle indices, and none in aged populations at high cardiovascular risk. We aimed to assess the association between CRC incidence and adherence to two emerging lifestyles indices (2018 WCRF/AICR score and another low-risk lifestyle (LRL) score comprising smoking status, alcohol consumption, physical activity, diet, and body mass index) in the Spanish PREvencion con DIeta MEDiterranea (PREDIMED) cohort. We studied 7216 elderly men and women at high cardiovascular risk. The 2018 WCRF/AICR and LRL scores were calculated. Multivariable Cox proportional regression models were fitted to estimate the HRs (hazard ratios) and 95% confidence intervals (CIs) for incident CRC events. During a median interquartile range (IQR) follow-up of 6.0 (4.4-7.3) years, 97 CRC events were considered. A significant linear association was observed between each 1-point increment in the WCRF/AICR score (score range from 0 to 7) and CRC risk (HR (95% CI) = 0.79 (0.63-0.99)). Similarly, each 1-point increment in the LRL score (score range from 0 to 5) was associated with a 22% reduction in CRC risk (0.78 (0.64-0.96)). Adhering to emergent lifestyle scores might substantially reduce CRC incidence in elderly individuals. Further longitudinal studies, which take different lifestyle indexes into account, are warranted in the future.
DOI de l'article:10.3390/jcm9041215
Enllaç font original:https://www.mdpi.com/2077-0383/9/4/1215
Versió de l'article dipositat:info:eu-repo/semantics/publishedVersion
Accès a la llicència d'ús:https://creativecommons.org/licenses/by/3.0/es/
Departament:Bioquímica i Biotecnologia
URL Document de llicència:https://repositori.urv.cat/ca/proteccio-de-dades/
Àrees temàtiques:Medicine, general & internal
Medicine (miscellaneous)
Medicine (all)
Paraules clau:Wcrf
Research fund/american institute
Recommendations
Prevention guidelines
Predimed
Physical-activity questionnaire
Metaanalysis
Low-risk lifestyle index
Lifestyle patterns
Insulin
Index
Dietary patterns
Concordance
Colorectal cancer
Aicr score
Adherence
wcrf/aicr score
predimed
lifestyle patterns
colorectal cancer
Entitat:Universitat Rovira i Virgili
Data d'alta del registre:2024-09-07
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