Autor/es de la URV: | Cano Lira, José Francisco / Guarro Artigas, Josep / Stchigel Glikman, Alberto Miguel / VALENZUELA LÓPEZ, NICOMEDES |
Autor según el artículo: | Valenzuela-Lopez, Nicomedes; Teresa Martin-Gomez, M.; Los-Arcos, Ibai; Stchigel, Alberto M.; Guarro, Josep; Cano-Lira, Jose F.; |
Direcció de correo del autor: | josep.guarro@urv.cat albertomiguel.stchigel@urv.cat jose.cano@urv.cat |
Identificador del autor: | 0000-0002-7839-7568 0000-0003-3987-7996 0000-0003-4495-4394 |
Año de publicación de la revista: | 2021 |
Tipo de publicación: | Journal Publications |
Referencia de l'ítem segons les normes APA: | Valenzuela-Lopez, Nicomedes; Teresa Martin-Gomez, M.; Los-Arcos, Ibai; Stchigel, Alberto M.; Guarro, Josep; Cano-Lira, Jose F.; (2021). A new pleosporalean fungus isolated from superficial to deep human clinical specimens. Medical Mycology, 59(3), 278-288. DOI: 10.1093/mmy/myaa055 |
Referencia al articulo segun fuente origial: | Medical Mycology. 59 (3): 278-288 |
Resumen: | Human infections by pleosporalean fungi (class Dothideomycetes, phylum Ascomycota) are rarely reported. Because their identification is challenging using morphological characterization, several phylogenetic markers must be sequenced for an accurate identification and taxonomical placement of the isolates. Three isolates of clinical origin were phenotypically characterized, but due to the absence of relevant morphological traits, D1-D2 domains of the 28S nrRNA gene (LSU), the internal transcribed spacer region (ITS) of the nrRNA, and fragments of the RNA polymerase II subunit 2 (rpb2) and translation elongation factor 1-alpha (tef1) genes were sequenced to allow a phylogenetic analysis that would solve their phylogenetic placement. That analysis revealed that these isolates did not match any previously known pleosporalean genera, and they are proposed here as the new fungal genus, Gambiomyces. Unfortunately, the isolates remained sterile, which, consequently, made the morphological description of the reproductive structures impossible. Future studies should try to understand the behaviour of this fungus in nature as well as its characteristics as an opportunistic fungal pathogen. Molecular identification is becoming an essential tool for proper identification of Dothideomycetes of clinical origin.
Lay Abstract
We describe a new pleosporalen pathogenic fungus, Gambiomyces profunda, found in superficial to deep samples from a human patient. Because all strains remained sterile, the fungus was finally identified following a phylogenetic analysis by using four different molecular markers. |
DOI del artículo: | 10.1093/mmy/myaa055 |
Enlace a la fuente original: | https://academic.oup.com/mmy/article-abstract/59/3/278/5876953?redirectedFrom=fulltext |
Versión del articulo depositado: | info:eu-repo/semantics/acceptedVersion |
Acceso a la licencia de uso: | https://creativecommons.org/licenses/by/3.0/es/ |
Departamento: | Ciències Mèdiques Bàsiques |
URL Documento de licencia: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
Áreas temáticas: | Zootecnia / recursos pesqueiros Veterinary sciences Veterinary (miscellaneous) Saúde coletiva Química Odontología Mycology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Infectious diseases Geografía General veterinary Farmacia Engenharias iii Engenharias ii Engenharias i Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotecnología Biodiversidade Astronomia / física |
Palabras clave: | Pleosporales Mycoses Infection Filamentous fungi Ascomycota |
Entidad: | Universitat Rovira i Virgili |
Fecha de alta del registro: | 2024-07-27 |
Descripción: | Human infections by pleosporalean fungi (class Dothideomycetes, phylum Ascomycota) are rarely reported. Because their identification is challenging using morphological characterization, several phylogenetic markers must be sequenced for an accurate identification and taxonomical placement of the isolates. Three isolates of clinical origin were phenotypically characterized, but due to the absence of relevant morphological traits, D1-D2 domains of the 28S nrRNA gene (LSU), the internal transcribed spacer region (ITS) of the nrRNA, and fragments of the RNA polymerase II subunit 2 (rpb2) and translation elongation factor 1-alpha (tef1) genes were sequenced to allow a phylogenetic analysis that would solve their phylogenetic placement. That analysis revealed that these isolates did not match any previously known pleosporalean genera, and they are proposed here as the new fungal genus, Gambiomyces. Unfortunately, the isolates remained sterile, which, consequently, made the morphological description of the reproductive structures impossible. Future studies should try to understand the behaviour of this fungus in nature as well as its characteristics as an opportunistic fungal pathogen. Molecular identification is becoming an essential tool for proper identification of Dothideomycetes of clinical origin.
Lay Abstract
We describe a new pleosporalen pathogenic fungus, Gambiomyces profunda, found in superficial to deep samples from a human patient. Because all strains remained sterile, the fungus was finally identified following a phylogenetic analysis by using four different molecular markers. |
Tipo: | Journal Publications |
Coautor: | Universitat Rovira i Virgili |
Títol: | A new pleosporalean fungus isolated from superficial to deep human clinical specimens |
Materia: | Infectious Diseases,Medicine (Miscellaneous),Mycology,Veterinary (Miscellaneous),Veterinary Sciences Pleosporales Mycoses Infection Filamentous fungi Ascomycota Zootecnia / recursos pesqueiros Veterinary sciences Veterinary (miscellaneous) Saúde coletiva Química Odontología Mycology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Infectious diseases Geografía General veterinary Farmacia Engenharias iii Engenharias ii Engenharias i Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotecnología Biodiversidade Astronomia / física |
Fecha: | 2021 |
Autor: | Valenzuela-Lopez, Nicomedes Teresa Martin-Gomez, M. Los-Arcos, Ibai Stchigel, Alberto M. Guarro, Josep Cano-Lira, Jose F. |
Derechos: | info:eu-repo/semantics/openAccess |
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