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Silicon-Based Laser Desorption Ionization Mass Spectrometry for the Analysis of Biomolecules: A Progress Report - imarina:9226662

Autor/es de la URV:Correig Blanchar, Francesc Xavier / Garcia-Altares Pérez, Maria / Ràfols Soler, Pere / Yanes Torrado, Óscar
Autor según el artículo:Alexandra Iakab, Stefania; Rafols, Pere; Garcia-Altares, Maria; Yanes, Oscar; Correig, Xavier
Direcció de correo del autor:oscar.yanes@urv.cat
maria.garcia-altares@urv.cat
pere.rafols@urv.cat
xavier.correig@urv.cat
Identificador del autor:0000-0003-3695-7157
0000-0002-9240-4058
0000-0002-6902-3054
Año de publicación de la revista:2019
Tipo de publicación:Journal Publications
Referencia de l'ítem segons les normes APA:Alexandra Iakab, Stefania; Rafols, Pere; Garcia-Altares, Maria; Yanes, Oscar; Correig, Xavier (2019). Silicon-Based Laser Desorption Ionization Mass Spectrometry for the Analysis of Biomolecules: A Progress Report. Advanced Functional Materials, 29(45), 1903609-. DOI: 10.1002/adfm.201903609
Referencia al articulo segun fuente origial:Advanced Functional Materials. 29 (45): 1903609-
Resumen:Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used in the biomedical field for the label-free analysis of molecules such as drugs, lipids, peptides, proteins, and biological tissues for molecular imaging. However, organic matrices used in traditional MALDI-MS applications introduce excessive interferences in the low m/z range. For this reason, nanostructured materials-and in particular silicon-based LDI strategies-have become a promising alternative, since they provide a much weaker background. Herein, the recent developments in fabrication, functionalization, and practical applications of silicon-based LDI-MS methods are reviewed. Also the basic requirements of silicon-based substrates for optimal LDI analysis by providing an overview of the LDI mechanisms that use silicon-based substrates instead of organic matrices are reported. Finally, the considerable potential of silicon-based substrates is discussed, giving suggestions for topics for future research.
DOI del artículo:10.1002/adfm.201903609
Enlace a la fuente original:https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201903609
Versión del articulo depositado:info:eu-repo/semantics/acceptedVersion
Acceso a la licencia de uso:https://creativecommons.org/licenses/by/3.0/es/
Departamento:Enginyeria Electrònica, Elèctrica i Automàtica
URL Documento de licencia:https://repositori.urv.cat/ca/proteccio-de-dades/
Áreas temáticas:Química
Physics, condensed matter
Physics, applied
Nanoscience and nanotechnology
Nanoscience & nanotechnology
Materials science, multidisciplinary
Materials science (miscellaneous)
Materials science (all)
Materiais
General materials science
General chemistry
Engenharias iv
Engenharias ii
Electronic, optical and magnetic materials
Electrochemistry
Condensed matter physics
Ciências agrárias i
Chemistry, physical
Chemistry, multidisciplinary
Chemistry (miscellaneous)
Chemistry (all)
Biomaterials
Astronomia / física
Palabras clave:Surface functionalization
Silver nanoparticles
Silicon nanostructures
Selective enrichment
Nanowire arrays
Nanostructure
Ms analysis
Modified porous silicon
Mass spectrometry imaging (msi)
Maldi
Laser desorption ionization (ldi)
Ion formation
High-sensitivity
Desorption/ionization
Entidad:Universitat Rovira i Virgili
Fecha de alta del registro:2024-10-12
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