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Effects of an organic diet intervention on the levels of organophosphorus metabolites in an adult cohort - imarina:9330537

Autor/s de la URV:Domingo Roig, José Luis / Gonzalez Paradell, Nieves / Marquès Bueno, Montserrat / Martínez Cánovas, Paula / Nadal Lomas, Martí
Autor segons l'article:González, N; Pàmies, C; Martinez, P; Martí, L; Domingo, JL; Nadal, M; Marquès, M
Adreça de correu electrònic de l'autor:marti.nadal@urv.cat
paula.martinez@urv.cat
nieves.gonzalez@urv.cat
montserrat.marques@urv.cat
paula.martinez@urv.cat
joseluis.domingo@urv.cat
marti.nadal@urv.cat
Identificador de l'autor:0000-0002-0217-4827
0000-0003-4134-016X
0000-0001-6302-8578
0000-0001-6647-9470
0000-0002-0217-4827
Any de publicació de la revista:2023
Tipus de publicació:Journal Publications
Referència de l'ítem segons les normes APA:González, N; Pàmies, C; Martinez, P; Martí, L; Domingo, JL; Nadal, M; Marquès, M (2023). Effects of an organic diet intervention on the levels of organophosphorus metabolites in an adult cohort. Food Research International, 173(Pt 1), 113354-113354. DOI: 10.1016/j.foodres.2023.113354
Referència a l'article segons font original:Food Research International. 173 (Pt 1): 113354-113354
Resum:Pesticides are a group of organic compounds used to control weeds or insect infestations in agriculture. Diet is the major route of human exposure to these compounds, which can cause serious health problems, even when the intake occurs at low concentrations. Hence, the consumption of organic food is an appropriate strategy to minimize the exposure to pesticides. A prospective, randomized study was conducted to assess the impact of an organic dietary intervention on the levels of urinary dialkyl phosphates (DAP). A screening of 204 pesticides was also carried out in order to confirm the absence of these compounds in organic food. The analytical results showed that only 20 of the 204 pesticides (9.8 %) had concentrations above the limit of quantification in one or more samples of the organic food consumed by the participants. It is substantially lower than the levels of pesticides found in other studies analysing conventional food, confirming the diet as suitable for the organic dietary intervention. A general reduction of most DAP metabolites in urine was found, being significant (p < 0.05) the decrease of dimethyl phosphate (DMP) (0.49 µg/g creatinine in Day 1 vs. 0.062 µg/g creatinine in Day 6), dimethyl thiophosphate (DMTP) (0.49 µg/g creatinine in Day 1 vs. 0.093 µg/g creatinine in Day 6) and diethyl phosphate (DEP) (0.28 µg/g creatinine in Day 1 vs. 0.12 µg/g creatinine in Day 6). In addition, the molar score for the total dimethyl DAP (ΣMP) and total dialkyl phosphate (ΣDAP) also showed significant differences after changing a conventional diet by an organic diet, being reduced from 0.008 µmol/g to 0.002 µmol/g for ΣMP and from 0.012 µmol/g to 0.003 µmol/g for ΣDAP. To the best of our knowledge, this is the first study that evaluates both the impact of an organic diet in the exposure to DAP and the levels of 204 pesticides in the organic food provided to the participants. In summary, the consumption of organic products decreases the dietary intake of pesticides, thus reducing also the potential adverse effects on human health.Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.
DOI de l'article:10.1016/j.foodres.2023.113354
Enllaç font original:https://www.sciencedirect.com/science/article/pii/S0963996923008992?via%3Dihub
Versió de l'article dipositat:info:eu-repo/semantics/publishedVersion
Accès a la llicència d'ús:https://creativecommons.org/licenses/by/3.0/es/
Departament:Ciències Mèdiques Bàsiques
URL Document de llicència:https://repositori.urv.cat/ca/proteccio-de-dades/
Àrees temàtiques:Zootecnia / recursos pesqueiros
Saúde coletiva
Química
Odontología
Nutrição
Medicina veterinaria
Medicina ii
Medicina i
Materiais
Matemática / probabilidade e estatística
Interdisciplinar
Food science & technology
Food science
Farmacia
Ensino
Engenharias iv
Engenharias iii
Engenharias ii
Engenharias i
Educação
Ciências biológicas iii
Ciências biológicas ii
Ciências biológicas i
Ciências ambientais
Ciências agrárias i
Ciência de alimentos
Ciência da computação
Biotecnología
Biodiversidade
Astronomia / física
Administração pública e de empresas, ciências contábeis e turismo
Paraules clau:Urine analysis
Pesticides
Organic food products
Dietary exposure
Dialkyl phosphates
Dialkyl phosphate metabolites
Biomonitoring
urine analysis
urinary concentrations
risk
residues
reduction
pesticides
pesticide metabolites
parameters
organic food products
exposure
dietary exposure
dialkyl phosphates
Entitat:Universitat Rovira i Virgili
Data d'alta del registre:2024-08-03
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