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TITLE:
Intensive Weight-Loss Lifestyle Intervention Using Mediterranean Diet and COVID-19 Risk in Older Adults: Secondary Analysis of PREDIMED-Plus Trial - imarina:9366633

URV's Author/s:Babio Sánchez, Nancy Elvira / García Gavilán, Jesús Francisco / Nishi, Stephanie Kimiko / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge / Shyam, Sangeetha
Author, as appears in the article.:Shyam, S; García-Gavilán, JF; Paz-Graniel, I; Gaforio, JJ; Martínez-González, MA; Corella, D; Martínez, JA; Alonso-Gómez, AM; Warnberg, J; Vioque, J; Romaguera, D; López-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, JL; Bueno-Cavanillas, A; Tur, JA; Sanchez, VM; Pinto, X; Matía-Martín, P; Vidal, J; Alcarria, MD; Daimiel, L; Ros, E; Fernandez-Aranda, F; Nishi, SK; Garcia-Regata, O; Araluce, RP; Asensio, EM; Castaner, O; Garcia-Rios, A; Oncina-Canovas, A; Bouzas, C; Zulet, MA; Rayo, E; Casas, R; Martin-Pelaez, S; Tojal-Sierra, L; Bernal-Lopez, MR; Carlos, S; Sorli, JV; Goday, A; Pena-Orihuela, PJ; Pastor-Morel, A; Eguaras, S; Zomeno, MD; Delgado-Rodriguez, M; Babio, N; Fito, M; Salas-Salvado, J
Author's mail:sangeetha.shyam@urv.cat
jesusfrancisco.garcia@urv.cat
stephanie.nishi@urv.cat
indiradelsocorro.paz@urv.cat
jesusfrancisco.garcia@urv.cat
indiradelsocorro.paz@urv.cat
jordi.salas@urv.cat
nancy.babio@urv.cat
Author identifier:0000-0002-3204-6877
0000-0002-3204-6877
0000-0003-2700-7459
0000-0003-3527-5277
Journal publication year:2023
Publication Type:Journal Publications
APA:Shyam, S; García-Gavilán, JF; Paz-Graniel, I; Gaforio, JJ; Martínez-González, MA; Corella, D; Martínez, JA; Alonso-Gómez, AM; Warnberg, J; Vioque, J; (2023). Intensive Weight-Loss Lifestyle Intervention Using Mediterranean Diet and COVID-19 Risk in Older Adults: Secondary Analysis of PREDIMED-Plus Trial. Journal Of Nutrition Health & Aging, 27(12), 1153-1161. DOI: 10.1007/s12603-023-2044-4
Papper original source:Journal Of Nutrition Health & Aging. 27 (12): 1153-1161
Abstract:ObjectivesWe tested the effects of a weight-loss intervention encouraging energy-reduced MedDiet and physical activity (PA) in comparison to ad libitum MedDiet on COVID-19 incidence in older adults.DesignSecondary analysis of PREDIMED-Plus, a prospective, ongoing, multicentre randomized controlled trial.SettingCommunity-dwelling, free-living participants in PREDIMED-Plus trial.Participants6,874 Spanish older adults (55-75 years, 49% women) with overweight/obesity and metabolic syndrome.InterventionParticipants were randomised to Intervention (IG) or Control (CG) Group. IG received intensive behavioural intervention for weight loss with an energy-reduced MedDiet intervention and PA promotion. CG was encouraged to consume ad libitum MedDiet without PA recommendations.MeasurementsCOVID-19 was ascertained by an independent Event Committee until December 31, 2021. COX regression models compared the effect of PREDIMED-Plus interventions on COVID-19 risk.ResultsOverall, 653 COVID-19 incident cases were documented (IG:317; CG:336) over a median (IQR) follow-up of 5.8 (1.3) years (inclusive of 4.0 (1.2) years before community transmission of COVID-19) in both groups. A significantly lowered risk of COVID-19 incidence was not evident in IG, compared to CG (fully-adjusted HR (95% CI): 0.96 (0.81,1.12)).ConclusionsThere was no evidence to show that an intensive weight-loss intervention encouraging energy-reduced MedDiet and PA significantly lowered COVID-19 risk in older adults with overweight/ obesity and metabolic syndrome in comparison to ad libitum MedDiet. Recommendations to improve adherence to MedDiet provided with or without lifestyle modification suggestions for weight loss may have similar effects in protecting against COVID-19 risk in older adults with high cardiovascular risks.
Article's DOI:10.1007/s12603-023-2044-4
Link to the original source:https://www.sciencedirect.com/science/article/pii/S1279770724002112?via%3Dihub
Papper version:info:eu-repo/semantics/publishedVersion
licence for use:https://creativecommons.org/licenses/by/3.0/es/
Department:Bioquímica i Biotecnologia
Licence document URL:https://repositori.urv.cat/ca/proteccio-de-dades/
Thematic Areas:Zootecnia / recursos pesqueiros
Saúde coletiva
Planejamento urbano e regional / demografia
Odontología
Nutrition and dietetics
Nutrition & dietetics
Nutrição
Medicine (miscellaneous)
Medicina iii
Medicina ii
Medicina i
Interdisciplinar
Geriatrics and gerontology
Geriatrics & gerontology
General medicine
Engenharias iii
Enfermagem
Educação física
Educação
Ciências biológicas ii
Ciências biológicas i
Ciências agrárias i
Ciência de alimentos
Keywords:Weight loss
Sars-cov2
Prospective studies
Predimed-plus
Overweight
Older adults
Obesity
Metabolic syndrome
Mediterranean diet
Male
Life style
Humans
Female
Diet, mediterranean
Covid-19
Cardiovascular diseases
Aged
Entity:Universitat Rovira i Virgili
Record's date:2024-08-03
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