Repositori institucional URV
| Autor/s de la URV: | Salas Huetos, Albert |
| Autor segons l'article: | Barranco I; Salas-Huetos A; Berlanga A; Spinaci M; Yeste M; Ribas-Maynou J |
| Adreça de correu electrònic de l'autor: | albert.salas@urv.cat |
| Identificador de l'autor: | 0000-0001-5914-6862 |
| Any de publicació de la revista: | 2022 |
| Tipus de publicació: | Journal Publications |
| Referència de l'ítem segons les normes APA: | Barranco I; Salas-Huetos A; Berlanga A; Spinaci M; Yeste M; Ribas-Maynou J (2022). Involvement of extracellular vesicle-encapsulated miRNAs in human reproductive disorders: a systematic review.. Reproduction Fertility And Development, 34(11), 751-775. DOI: 10.1071/RD21301 |
| Referència a l'article segons font original: | Reproduction Fertility And Development. 34 (11): 751-775 |
| Resum: | In recent years, extracellular vesicles (EVs) have emerged as essential players in cell-to-cell communication, particularly having an active regulating role in biological systems. Because reproductive-associated processes are not exempt of this communication, multiple studies have been devoted to this realm, focusing on gamete maturation, embryo implantation or fetal development. The aim of the present review was to comprehensively and systematically collect evidence about the function of the microRNA (miRNA) encapsulated in EVs isolated from different reproductive tissues or fluids in reproductive-related diseases. Following PRISMA guidelines, we conducted a systematic search of the literature published in MEDLINE-PubMed until the end of February 2021. After selection, 32 studies were included in the qualitative review comparing the miRNA expression profile in EVs between different pathological disorders. Most reports showed the potential of the miRNAs carried by EVs to be used as putative biomarkers of reproductive disorders, including pregnancy affections, disease progression and quality of preimplantation embryos. The most relevant miRNAs were found to be highly heterogeneous among studies, with some conflicting results. Further research is thus warranted to address whether cofounding factors, such as the methods to isolate EVs and miRNAs, the subset of EVs, the criteria of patient selection, the timing of sample retrieval, or any other factor, may explain the inconsistencies between studies. |
| DOI de l'article: | 10.1071/RD21301 |
| Enllaç font original: | https://www.publish.csiro.au/RD/RD21301 |
| Versió de l'article dipositat: | info:eu-repo/semantics/acceptedVersion |
| Accès a la llicència d'ús: | https://creativecommons.org/licenses/by/3.0/es/ |
| Departament: | Ciències Mèdiques Bàsiques |
| URL Document de llicència: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Àrees temàtiques: | Animal science and zoology Biodiversidade Biotechnology Biotecnología Ciências agrárias i Ciências ambientais Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Developmental biology Endocrinology Farmacia Genetics Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Medicine (all) Molecular biology Odontología Psicología Química Reproductive biology Reproductive medicine Zoology Zootecnia / recursos pesqueiros |
| Paraules clau: | Blastocyst Cell communication Embryo implantation Extracellular vesicles Female Humans Micrornas Pregnancy |
| Entitat: | Universitat Rovira i Virgili |
| Data d'alta del registre: | 2024-07-20 |
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| Fitxer | Descripció | Format | |
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| DocumentPrincipal | DocumentPrincipal | application/pdf |
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