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Early-life chemical exposome: Comprehensive strategies for wide-scope screening of organic compounds - imarina:9379704

Autor/es de la URV:Ramírez González, Noelia / Vinaixa Crevillent, Maria
Autor según el artículo:Guerrini, C; Escribano, J; Ramírez, N; Vinaixa, M; Sunyer-Caldú, A; Gil-Solsona, R; Gago-Ferrero, P
Direcció de correo del autor:maria.vinaixa@urv.cat
Identificador del autor:0000-0001-9804-0171
Año de publicación de la revista:2024
Tipo de publicación:Journal Publications
Referencia de l'ítem segons les normes APA:Guerrini, C; Escribano, J; Ramírez, N; Vinaixa, M; Sunyer-Caldú, A; Gil-Solsona, R; Gago-Ferrero, P (2024). Early-life chemical exposome: Comprehensive strategies for wide-scope screening of organic compounds. Trac-Trends In Analytical Chemistry, 180(), 117903-. DOI: 10.1016/j.trac.2024.117903
Referencia al articulo segun fuente origial:Trac-Trends In Analytical Chemistry. 180 117903-
Resumen:Exposure to organic compounds during early-life stages can disrupt human development and increase susceptibility to adverse health outcomes later in life. Despite evidence of these impacts, research has primarily focused on targeted analyses, missing the complex nature of early-life exposures. Comprehensive approaches are needed to better characterize these complex mixtures. Recent advances in high-resolution mass spectrometry and computational science have enabled the comprehensive analysis of numerous chemicals through wide-scope screening approaches, yet their application in early-life exposome studies is still limited. This review critically examines studies from the past decade using wide-scope screening to investigate the early-life chemical exposome, emphasizing organic compounds. It evaluates each step of the analytical workflow, including sample collection, preparation, analysis, and data processing, and concludes with recommendations for future research to improve understanding of the early-life chemical exposome and its health implications.
DOI del artículo:10.1016/j.trac.2024.117903
Enlace a la fuente original:https://www.sciencedirect.com/science/article/pii/S0165993624003868
Versión del articulo depositado:info:eu-repo/semantics/publishedVersion
Acceso a la licencia de uso:https://creativecommons.org/licenses/by/3.0/es/
Departamento:Enginyeria Electrònica, Elèctrica i Automàtica
URL Documento de licencia:https://repositori.urv.cat/ca/proteccio-de-dades/
Áreas temáticas:Spectroscopy
Química
Medicina ii
Interdisciplinar
Farmacia
Environmental chemistry
Engenharias iv
Engenharias iii
Engenharias ii
Ciências biológicas ii
Ciências biológicas i
Ciências ambientais
Ciências agrárias i
Ciência de alimentos
Chemistry, analytical
Biotecnología
Astronomia / física
Analytical chemistry
Palabras clave:Wide-scope screening
Suspect screening analysis
Suspect screening analysi
Suspect
Substances
Non-targeted analysis
Metabolites
Human exposure
High-resolution mass spectrometry
Health
Exposomics
Environmental chemicals
Early-life
Current knowledge
Contaminants
Chemical exposome
Challeng
Biomarkers
Entidad:Universitat Rovira i Virgili
Fecha de alta del registro:2024-09-14
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