Autor segons l'article: Montserrat Diéguez Oscar Pàmies MARIA BIOSCA Carlota Borràs
Departament: Química Física i Inorgànica
Autor/s de la URV: DIÉGUEZ FERNÁNDEZ, MONTSERRAT PAMIES OLLÉ, OSCAR MARIA BIOSCA BORRÀS NOGUERA, CARLOTA
Paraules clau: reaction intermediates asymmetric catalysis iridium
Resum: We report a reduced but structurally valuable
phosphite/phosphinite-thioether ligand library for the Irhydrogenation
of 40 minimally functionalized alkenes,
including relevant examples with poorly coordinative groups.
We found that enantiomeric excesses are mainly dependent on
the substrate structure and on some ligand parameters (i.e., the
type of thioether/phosphorus moieties and the configuration of
the phosphite group), whereas the substituents of the biaryl
phosphite moiety had little impact. By tuning the ligand
parameters we were able to find highly selective catalysts for a
range of substrates (ee’s up to 99%). These phosphite/phosphinite-thioether ligands have a simple backbone and thus yield
simple NMR spectra that reduce signal overlap and facilitate the identification of relevant intermediates. Therefore, by combining
HP-NMR spectroscopy and theoretical studies, we were also able to identify the catalytically competent Ir-dihydride alkene
species, which made it possible to explain the enantioselectivity obtained.
Grup de recerca: Organometàl.lics i Catàlisi Homogènia
Àrees temàtiques: Chemistry Química Química
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0276-7333
Identificador de l'autor: 0000-0002-8450-0656 0000-0002-2352-8508 n/a n/a
Data d'alta del registre: 2015-11-18
Pàgina final: 5334
Volum de revista: 34
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://pubs.acs.org/doi/10.1021/acs.organomet.5b00790
DOI de l'article: 10.1021/acs.organomet.5b00790
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2015
Pàgina inicial: 5321
Tipus de publicació: Post-print
Repositori URV