Autor segons l'article: Montserrat Diéguez Sabina Alegre Yvette Mata Oscar Pàmies
Departament: Química Física i Inorgànica
Autor/s de la URV: DIÉGUEZ FERNÁNDEZ, MONTSERRAT Sabina Alegre Yvette Mata PAMIES OLLÉ, OSCAR
Paraules clau: asymmetric catalysis palladium allylic substitution
Resum: We have applied a modular sugar-based
phosphite ligand library for the Pd-catalyzed allylic
substitution reactions of several substrates. These ligands
are derived from D-(+)-glucose, D-(+)-galactose and D-(+)-
fructose, which lead to a wide range of sugar backbones,
and contain several substituents at the C-3 carbon of
the furanoside backbone and several substituents/
configurations in the biaryl moiety, with different steric
and electronic properties. Systematic variation of the
ligand parameters indicates that the catalytic performance
(activities and enantioselectivities) is highly affected by
sugar backbone, the substituents at the C-3 carbon of
the furanoside backbone, the configurations at the C-3
and C-4 carbons of the ligand backbone and the type
of substituents/configurations in the biaryl phosphite
moiety as well as the substrate type. For disubstituted
substrates moderate enantioselectivities (up to 72%) were
achieved using ligand L8d, while for monosubstituted
substrates the highest enantioselectivities (up to 40%)
were obtained using ligand L9a
Grup de recerca: Organometàl.lics i Catàlisi Homogènia
Àrees temàtiques: Química Química Chemistry
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 2300-4630
Identificador de l'autor: 0000-0002-8450-0656 n/a n/a 0000-0002-2352-8508
Data d'alta del registre: 2015-11-18
Pàgina final: 39
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2014
Pàgina inicial: 32
Tipus de publicació: Article
Repositori URV