Articles producció científica> Medicina i Cirurgia

Virgin Olive Oil Enriched with Its Own Phenols or Complemented with Thyme Phenols Improves DNA Protection against Oxidation and Antioxidant Enzyme Activity in Hyperlipidemic Subjects

  • Dades identificatives

    Identificador: PC:1516
    Autors:
    Marta RomeuLaura RubióVanessa Sánchez-MartosOlga CastanerRafael de la TorreRosa M. VallsRosa RasAnna PedretÚrsula CatalánMaría del Carmen López de las HazasMaría J. MotilvaMontserrat FitoRosa SolàMontserrat Giralt
    Resum:
    DOI: 10.1021/acs.jafc.5b04915
  • Altres:

    Autor segons l'article: Marta Romeu; Laura Rubió; Vanessa Sánchez-Martos; Olga Castaner; Rafael de la Torre; Rosa M. Valls; Rosa Ras; Anna Pedret; Úrsula Catalán; María del Carmen López de las Hazas; María J. Motilva; Montserrat Fito; Rosa Solà; Montserrat Giralt
    Departament: Medicina i Cirurgia Ciències Mèdiques Bàsiques
    Autor/s de la URV: ROMEU FERRAN, MARTA; Laura Rubio; SÁNCHEZ MARTOS, VANESSA; Olga Castan¿er; Rafael de la Torre; VALLS ZAMORA, ROSA MARIA; Rosa Ras; PEDRET FIGUEROLA, ANNA; CATALÁN SANTOS, ÚRSULA; María del Carmen Lo¿pez de las Hazas; María J. Motilva; Montserrat Fito; SOLÀ ALBERICH, ROSA MARIA; GIRALT BATISTA, MONTSERRAT
    Paraules clau: phenol enrichment thyme phenols virgin olive oil
    Resum: The effects of virgin olive oil (VOO) enriched with its own phenolic compounds (PC) and/or thyme PC on the protection against oxidative DNA damage and antioxidant endogenous enzymatic system (AEES) were estimated in 33 hyperlipidemic subjects after the consumption of VOO, VOO enriched with its own PC (FVOO), or VOO complemented with thyme PC (FVOOT). Compared to pre-intervention, 8-hydroxy-2′-deoxyguanosine (a marker for DNA damage) decreased in the FVOO intervention and to a greater extent in the FVOOT with a parallel significant increase in olive and thyme phenolic metabolites. Superoxide dismutase (AEES enzyme) significantly increased in the FVOO intervention and to a greater extent in the FVOOT with a parallel significant increase in thyme phenolic metabolites. When all three oils were compared, FVOOT appeared to have the greatest effect in protecting against oxidative DNA damage and improving AEES. The sustained intake of a FVOOT improves DNA protection against oxidation and AEES probably due to a greater bioavailability of thyme PC in hyperlipidemic subjects.
    Grup de recerca: Farmacobiologia Cel.lular Unitat de Recerca de Lípids i Arteriosclerosi
    Àrees temàtiques: Ciències de la salut Ciencias de la salud Health sciences
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0021-8561
    Identificador de l'autor: orcid.org/0000-0002-2131-1858; N/D; N/D; N/D; N/D; N/D; N/D; orcid.org/0000-0002-5327-932X; N/D; orcid.org/0000-0001-8199-6724; N/D; orcid.org/0000-0002-1817-483X; orcid.org/0000-0002-8359-235X; orcid.org/0000-0002-7073-577X
    Data d'alta del registre: 2016-05-12
    Pàgina final: 1888
    Volum de revista: 64
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    Enllaç font original: https://pubs.acs.org/doi/10.1021/acs.jafc.5b04915
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.1021/acs.jafc.5b04915
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2016
    Pàgina inicial: 1879
    Tipus de publicació: Article Artículo Article
  • Paraules clau:

    Oli d'oliva
    Fenols
    Hiperlipèmia
    phenol enrichment
    thyme phenols
    virgin olive oil
    Ciències de la salut
    Ciencias de la salud
    Health sciences
    0021-8561
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