Autor segons l'article: Andrade, F.J.; Parrilla, M.; Cánovas, R.
Departament: Química Analítica i Química Orgànica
Autor/s de la URV: ANDRADE , FRANCISCO JAVIER; Parrilla, M.; Cánovas, R.
Resum: A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of -119±8 mV·decade-1, a linear range that spans from 10-4M to 10-2.5 M and a limit of detection of 10-4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.
Grup de recerca: Grup de Quimiometria, Qualimetria i Nanosensors
Àrees temàtiques: Química Química Chemistry
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0956-5663
Identificador de l'autor: 0000-0003-1199-2837; 0000-0002-1344-8432; 0000-0001-9552-535X
Data d'alta del registre: 2018-04-30
Versió de l'article dipositat: info:eu-repo/semantics/submittedVersion
Enllaç font original: https://www.sciencedirect.com/science/article/pii/S0956566316311745?via%3Dihub
Programa de finançament: plan; CTQ2013-46464-R altres; EU-Marie Curie Grant; PCIG09-GA-2011-293538 altres; Gencat fellowship; FI; FI_B 00079 altres; URV Martí i Franqués; PMF-PIPF; 2013PMF-PIPF-16
DOI de l'article: 10.1016/j.bios.2016.11.034
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2016
Tipus de publicació: Article Artículo Article
Repositori URV