Articles producció científica> Medicina i Cirurgia

Does the Mediterranean diet counteract the adverse effects of abdominal adiposity?

  • Dades identificatives

    Identificador: imarina:2092574
    Autors:
    Eguaras, SToledo, EBuil-Cosiales, PSalas-Salvado, JCorella, DGutierrez-Bedmar, MSantos-Lozano, J MAros, FFiol, MFito, MRos, ESerra-Majem, LPinto, XMartinez, J ASorli, J VMunoz, M ABasora, JEstruch, RMartinez-Gonzalez, M A
    Resum:
    We tested the hypothesis that an intervention with a Mediterranean diet (MeDiet) could mitigate the well-known harmful effects of abdominal obesity on cardiovascular health.We assessed the relationship between baseline waist-to-height ratio (WHtR) and major cardiovascular events during a median follow-up of 4.8 years in the Prevention with Mediterranean Diet (PREDIMED) randomized primary prevention trial, which tested a MeDiet against a control diet (advice on a low-fat diet). We also examined whether the MeDiet intervention was able to counteract the detrimental cardiovascular effects of an increased WHtR. The trial included 7447 participants (55-80 years old, 57% women) at high cardiovascular risk but free of cardiovascular disease (CVD) at enrollment. An increased risk of CVD events (myocardial infarction, stroke, or cardiovascular death) was apparent for the highest versus the lowest quartile of WHtR (multivariable-adjusted hazard ratio: 1.98) (95% confidence interval: 1.10-3.57; linear trend: p = 0.019) only in the control-diet group, but not in the two groups allocated to intervention with MeDiet (p for interaction = 0.034). This apparent interaction suggesting that the intervention counterbalanced the detrimental cardiovascular effects of adiposity was also significant for body mass index (BMI) (p = 0.01) and waist circumference (p = 0.043).The MeDiet may counteract the harmful effects of increased adiposity on the risk of CVD.Copyright © 2015 Elsevier B.V. All rights reserved.
  • Altres:

    Autor segons l'article: Eguaras, S; Toledo, E; Buil-Cosiales, P; Salas-Salvado, J; Corella, D; Gutierrez-Bedmar, M; Santos-Lozano, J M; Aros, F; Fiol, M; Fito, M; Ros, E; Serra-Majem, L; Pinto, X; Martinez, J A; Sorli, J V; Munoz, M A; Basora, J; Estruch, R; Martinez-Gonzalez, M A
    Departament: Medicina i Cirurgia Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia
    Autor/s de la URV: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Cabre Vila, Juan Jose / Fernández Ballart, Joan Domènech / Salas Salvadó, Jorge
    Paraules clau: Waist-to-height ratio Waist to height ratio Waist circumference Treatment outcome Time factors Spain Risk factors Randomized controlled trial Protective factors Proportional hazards models Priority journal Primary prevention Physical activity Obesity, abdominal Non insulin dependent diabetes mellitus Multivariate analysis Multicenter study Middle aged Mediterranean diet Male Major clinical study Lifestyle Incidence Humans Human Heart infarction Follow up Female Dietary intervention Diet, mediterranean Demography Controlled study Cardiovascular risk Cardiovascular diseases Cardiovascular disease Body mass index Body mass Article Aged, 80 and over Aged Adult Adiposity Abdominal obesity mediterranean diet dietary intervention cardiovascular disease
    Resum: We tested the hypothesis that an intervention with a Mediterranean diet (MeDiet) could mitigate the well-known harmful effects of abdominal obesity on cardiovascular health.We assessed the relationship between baseline waist-to-height ratio (WHtR) and major cardiovascular events during a median follow-up of 4.8 years in the Prevention with Mediterranean Diet (PREDIMED) randomized primary prevention trial, which tested a MeDiet against a control diet (advice on a low-fat diet). We also examined whether the MeDiet intervention was able to counteract the detrimental cardiovascular effects of an increased WHtR. The trial included 7447 participants (55-80 years old, 57% women) at high cardiovascular risk but free of cardiovascular disease (CVD) at enrollment. An increased risk of CVD events (myocardial infarction, stroke, or cardiovascular death) was apparent for the highest versus the lowest quartile of WHtR (multivariable-adjusted hazard ratio: 1.98) (95% confidence interval: 1.10-3.57; linear trend: p = 0.019) only in the control-diet group, but not in the two groups allocated to intervention with MeDiet (p for interaction = 0.034). This apparent interaction suggesting that the intervention counterbalanced the detrimental cardiovascular effects of adiposity was also significant for body mass index (BMI) (p = 0.01) and waist circumference (p = 0.043).The MeDiet may counteract the harmful effects of increased adiposity on the risk of CVD.Copyright © 2015 Elsevier B.V. All rights reserved.
    Àrees temàtiques: Serviço social Saúde coletiva Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Enfermagem Endocrinology, diabetes and metabolism Endocrinology & metabolism Educação física Ciências biológicas ii Ciências biológicas i Ciências ambientais Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 15903729
    Adreça de correu electrònic de l'autor: juanjose.cabre@urv.cat josep.basora@urv.cat josep.basora@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
    Identificador de l'autor: 0000-0003-1082-6861 0000-0003-2700-7459 0000-0003-3527-5277
    Data d'alta del registre: 2024-10-19
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    Enllaç font original: https://www.nmcd-journal.com/article/S0939-4753(15)00057-5/abstract
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Nutrition Metabolism And Cardiovascular Diseases. 25 (6): 569-574
    Referència de l'ítem segons les normes APA: Eguaras, S; Toledo, E; Buil-Cosiales, P; Salas-Salvado, J; Corella, D; Gutierrez-Bedmar, M; Santos-Lozano, J M; Aros, F; Fiol, M; Fito, M; Ros, E; Ser (2015). Does the Mediterranean diet counteract the adverse effects of abdominal adiposity?. Nutrition Metabolism And Cardiovascular Diseases, 25(6), 569-574. DOI: 10.1016/j.numecd.2015.03.001
    DOI de l'article: 10.1016/j.numecd.2015.03.001
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2015
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Cardiac & Cardiovascular Systems,Cardiology and Cardiovascular Medicine,Endocrinology & Metabolism,Endocrinology, Diabetes and Metabolism,Medicine (Miscellaneous),Nutrition & Dietetics,Nutrition and Dietetics
    Waist-to-height ratio
    Waist to height ratio
    Waist circumference
    Treatment outcome
    Time factors
    Spain
    Risk factors
    Randomized controlled trial
    Protective factors
    Proportional hazards models
    Priority journal
    Primary prevention
    Physical activity
    Obesity, abdominal
    Non insulin dependent diabetes mellitus
    Multivariate analysis
    Multicenter study
    Middle aged
    Mediterranean diet
    Male
    Major clinical study
    Lifestyle
    Incidence
    Humans
    Human
    Heart infarction
    Follow up
    Female
    Dietary intervention
    Diet, mediterranean
    Demography
    Controlled study
    Cardiovascular risk
    Cardiovascular diseases
    Cardiovascular disease
    Body mass index
    Body mass
    Article
    Aged, 80 and over
    Aged
    Adult
    Adiposity
    Abdominal obesity
    mediterranean diet
    dietary intervention
    cardiovascular disease
    Serviço social
    Saúde coletiva
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Farmacia
    Enfermagem
    Endocrinology, diabetes and metabolism
    Endocrinology & metabolism
    Educação física
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Cardiology and cardiovascular medicine
    Cardiac & cardiovascular systems
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